Place cells and long-term potentiation in the hippocampus

LF Cobar, L Yuan, A Tashiro - Neurobiology of learning and memory, 2017 - Elsevier
Place cells show location-specific firing patterns according to an animal's position in an
environment and are thought to contribute to the spatial representation required for self …

Role of the GRP/GRPR system in regulating brain functions

T Zhao, A Chen, D Dai, Z Li, XF Gao… - ACS Chemical …, 2023 - ACS Publications
Re-examining the relationship between neuropeptide systems and neural circuits will help
us to understand more intensively the critical role of neuropeptides in brain function as the …

[图书][B] Engineering the next revolution in neuroscience: The new science of experiment planning

AJ Silva, A Landreth, J Bickle - 2013 - books.google.com
Science is growing at a pace that exceeds our comprehension. This is no less true of
neuroscience than any other discipline. Ambiguity about what is known and what has been …

Chronic stress alters spatial representation and bursting patterns of place cells in behaving mice

M Park, CH Kim, S Jo, EJ Kim, H Rhim, CJ Lee… - Scientific reports, 2015 - nature.com
Chronic uncontrollable stress has been shown to produce various physiological alterations
and impair mnemonic functions in the rodent hippocampus. Impacts on neuronal activities …

Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced …

XD Yu, TH Ren, XG Yu - British journal of nutrition, 2013 - cambridge.org
Maternal dietary Zn deficiency during fetal development induces substantial cognitive
dysfunctions in the resultant offspring. The mechanism underlying this effect is unclear. The …

Conditional knockout of Cav2. 1 disrupts the accuracy of spatial recognition of CA1 place cells and Spatial/Contextual recognition behavior

D Jung, YJ Hwang, H Ryu, M Kano… - Frontiers in Behavioral …, 2016 - frontiersin.org
Hippocampal pyramidal neurons play an essential role in processing spatial information as
implicated with its place-dependent firing. Although, previous slice physiology studies have …

CA1 spike timing is impaired in the 129S inbred strain during cognitive tasks

T Adeyelu, A Shrestha, PA Adeniyi, CC Lee… - Neuroscience, 2022 - Elsevier
A spontaneous mutation of the disrupted in schizophrenia 1 (Disc1) gene is carried by the
129S inbred mouse strain. Truncated DISC1 protein in 129S mouse synapses impairs the …

[HTML][HTML] Datumetine preferentially upregulates N-methyl-D-aspartate receptor signalling pathways in different brain regions of mice

AO Ishola, AE Adetunji, IC Abanum… - Basic and clinical …, 2023 - ncbi.nlm.nih.gov
Methods: 30 male adult BALB/c mice were used for the study. The mice were randomly
divided into three groups of ten mice each with an intraperitoneal injection of 0.1 mL of 10 …

Inducible knockout of the cyclin-dependent kinase 5 activator p35 alters hippocampal spatial coding and neuronal excitability

E Kamiki, R Boehringer, D Polygalov… - Frontiers in Cellular …, 2018 - frontiersin.org
p35 is an activating co-factor of Cyclin-dependent kinase 5 (Cdk5), a protein whose
dysfunction has been implicated in a wide-range of neurological disorders including …

[HTML][HTML] Datumetine Preferentially Upregulates N-methyl-Daspartate Receptor Signalling Pathways in Different Brain Regions of Mice

IA Olakunle, AA Enitan, AI Chukwunwike, AA Akorede… - 2023 - sid.ir
Introduction: We previously reported that Datumetine possesses binding affinity with N-
methyl-D-aspartate receptor (NMDAR) and that 14-day exposure to Datumetine altered …