Place cells and long-term potentiation in the hippocampus
Place cells show location-specific firing patterns according to an animal's position in an
environment and are thought to contribute to the spatial representation required for self …
environment and are thought to contribute to the spatial representation required for self …
Role of the GRP/GRPR system in regulating brain functions
T Zhao, A Chen, D Dai, Z Li, XF Gao… - ACS Chemical …, 2023 - ACS Publications
Re-examining the relationship between neuropeptide systems and neural circuits will help
us to understand more intensively the critical role of neuropeptides in brain function as the …
us to understand more intensively the critical role of neuropeptides in brain function as the …
[图书][B] Engineering the next revolution in neuroscience: The new science of experiment planning
Science is growing at a pace that exceeds our comprehension. This is no less true of
neuroscience than any other discipline. Ambiguity about what is known and what has been …
neuroscience than any other discipline. Ambiguity about what is known and what has been …
Chronic stress alters spatial representation and bursting patterns of place cells in behaving mice
Chronic uncontrollable stress has been shown to produce various physiological alterations
and impair mnemonic functions in the rodent hippocampus. Impacts on neuronal activities …
and impair mnemonic functions in the rodent hippocampus. Impacts on neuronal activities …
Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced …
XD Yu, TH Ren, XG Yu - British journal of nutrition, 2013 - cambridge.org
Maternal dietary Zn deficiency during fetal development induces substantial cognitive
dysfunctions in the resultant offspring. The mechanism underlying this effect is unclear. The …
dysfunctions in the resultant offspring. The mechanism underlying this effect is unclear. The …
Conditional knockout of Cav2. 1 disrupts the accuracy of spatial recognition of CA1 place cells and Spatial/Contextual recognition behavior
Hippocampal pyramidal neurons play an essential role in processing spatial information as
implicated with its place-dependent firing. Although, previous slice physiology studies have …
implicated with its place-dependent firing. Although, previous slice physiology studies have …
CA1 spike timing is impaired in the 129S inbred strain during cognitive tasks
A spontaneous mutation of the disrupted in schizophrenia 1 (Disc1) gene is carried by the
129S inbred mouse strain. Truncated DISC1 protein in 129S mouse synapses impairs the …
129S inbred mouse strain. Truncated DISC1 protein in 129S mouse synapses impairs the …
[HTML][HTML] Datumetine preferentially upregulates N-methyl-D-aspartate receptor signalling pathways in different brain regions of mice
AO Ishola, AE Adetunji, IC Abanum… - Basic and clinical …, 2023 - ncbi.nlm.nih.gov
Methods: 30 male adult BALB/c mice were used for the study. The mice were randomly
divided into three groups of ten mice each with an intraperitoneal injection of 0.1 mL of 10 …
divided into three groups of ten mice each with an intraperitoneal injection of 0.1 mL of 10 …
Inducible knockout of the cyclin-dependent kinase 5 activator p35 alters hippocampal spatial coding and neuronal excitability
E Kamiki, R Boehringer, D Polygalov… - Frontiers in Cellular …, 2018 - frontiersin.org
p35 is an activating co-factor of Cyclin-dependent kinase 5 (Cdk5), a protein whose
dysfunction has been implicated in a wide-range of neurological disorders including …
dysfunction has been implicated in a wide-range of neurological disorders including …
[HTML][HTML] Datumetine Preferentially Upregulates N-methyl-Daspartate Receptor Signalling Pathways in Different Brain Regions of Mice
IA Olakunle, AA Enitan, AI Chukwunwike, AA Akorede… - 2023 - sid.ir
Introduction: We previously reported that Datumetine possesses binding affinity with N-
methyl-D-aspartate receptor (NMDAR) and that 14-day exposure to Datumetine altered …
methyl-D-aspartate receptor (NMDAR) and that 14-day exposure to Datumetine altered …