Ultrasound microbubble contrast agents: fundamentals and application to gene and drug delivery
This review offers a critical analysis of the state of the art of medical microbubbles and their
application in therapeutic delivery and monitoring. When driven by an ultrasonic pulse …
application in therapeutic delivery and monitoring. When driven by an ultrasonic pulse …
Quantitative contrast-enhanced ultrasound imaging: a review of sources of variability
Ultrasound provides a valuable tool for medical diagnosis offering real-time imaging with
excellent spatial resolution and low cost. The advent of microbubble contrast agents has …
excellent spatial resolution and low cost. The advent of microbubble contrast agents has …
In situ conversion of porphyrin microbubbles to nanoparticles for multimodality imaging
Converting nanoparticles or monomeric compounds into larger supramolecular structures by
endogenous, or external, stimuli is increasingly popular because these materials are useful …
endogenous, or external, stimuli is increasingly popular because these materials are useful …
Gain an advantage from both sides: Smart size-shrinkable drug delivery nanosystems for high accumulation and deep penetration
The first generation of nanomedicine exhibits superior performance in the clinical treatment
of various cancers compared to free conventional anticancer therapeutics. However, poor …
of various cancers compared to free conventional anticancer therapeutics. However, poor …
Response of contrast agents to ultrasound
V Sboros - Advanced drug delivery reviews, 2008 - Elsevier
Microbubbles are used as ultrasonic contrast agents that enhance the ultrasound signals of
the vascular bed. The recent development of site-targeted microbubbles opened up the …
the vascular bed. The recent development of site-targeted microbubbles opened up the …
Growth and dissolution of an encapsulated contrast microbubble: effects of encapsulation permeability
Gas diffusion from an encapsulated microbubble is modeled using an explicit linear relation
for gas permeation through the encapsulation. Both the cases of single gas (air) and multiple …
for gas permeation through the encapsulation. Both the cases of single gas (air) and multiple …
Effects of encapsulation elasticity on the stability of an encapsulated microbubble
A model for gas transport from an encapsulated microbubble into the surrounding medium is
developed and investigated incorporating the effects of encapsulation elasticity …
developed and investigated incorporating the effects of encapsulation elasticity …
Ultrasound-mediated destruction of contrast microbubbles used for medical imaging and drug delivery
D Chatterjee, P Jain, K Sarkar - Physics of Fluids, 2005 - pubs.aip.org
Micron-size bubbles encapsulated by a stabilizing layer of surface-active materials are used
in medical ultrasound imaging and drug delivery. Their destruction stimulated by ultrasound …
in medical ultrasound imaging and drug delivery. Their destruction stimulated by ultrasound …
The behaviour of individual contrast agent microbubbles
V Sboros, CM Moran, SD Pye, WN McDicken - Ultrasound in medicine & …, 2003 - Elsevier
In recent years, our knowledge of the behaviour of ultrasonic microbubble contrast agents
has improved substantially through in vitro experiments. However, there has been a …
has improved substantially through in vitro experiments. However, there has been a …
Destruction thresholds of echogenic liposomes with clinical diagnostic ultrasound
Echogenic liposomes (ELIP) are submicron-sized phospholipid vesicles that contain both
gas and fluid. With antibody conjugation and drug incorporation, these liposomes can be …
gas and fluid. With antibody conjugation and drug incorporation, these liposomes can be …