Stepping on the gas to a circular economy: accelerating development of carbon-negative chemical production from gas fermentation

N Fackler, BD Heijstra, BJ Rasor… - Annual review of …, 2021 - annualreviews.org
Owing to rising levels of greenhouse gases in our atmosphere and oceans, climate change
poses significant environmental, economic, and social challenges globally. Technologies …

Pollution to products: recycling of 'above ground'carbon by gas fermentation

M Köpke, SD Simpson - Current Opinion in Biotechnology, 2020 - Elsevier
Climate crisis and rapid population growth are posing some of the most urgent challenges to
mankind and have intensified the need for the deployment of carbon recycling and carbon …

Approaches to genetic tool development for rapid domestication of non-model microorganisms

LA Riley, AM Guss - Biotechnology for Biofuels, 2021 - Springer
Non-model microorganisms often possess complex phenotypes that could be important for
the future of biofuel and chemical production. They have received significant interest the last …

De novo biosynthesis of butyl butyrate in engineered Clostridium tyrobutyricum

X Guo, H Zhang, J Feng, L Yang, K Luo, H Fu… - Metabolic …, 2023 - Elsevier
Butyl butyrate has broad applications in foods, cosmetics, solvents, and biofuels. Microbial
synthesis of bio-based butyl butyrate has been regarded as a promising approach recently …

Toward improved terpenoids biosynthesis: strategies to enhance the capabilities of cell factories

E Fordjour, EO Mensah, Y Hao, Y Yang, X Liu… - Bioresources and …, 2022 - Springer
Terpenoids form the most diversified class of natural products, which have gained
application in the pharmaceutical, food, transportation, and fine and bulk chemical …

Engineering Clostridium organisms as microbial cell-factories: challenges & opportunities

K Charubin, RK Bennett, AG Fast, ET Papoutsakis - Metabolic engineering, 2018 - Elsevier
Clostridium organisms are of major importance in the development of technologies to
produce biofuels and chemicals. They are uniquely capable of utilizing virtually all biomass …

A Strongly Fluorescing Anaerobic Reporter and Protein-Tagging System for Clostridium Organisms Based on the Fluorescence-Activating and Absorption-Shifting …

HE Streett, KM Kalis… - Applied and Environmental …, 2019 - Am Soc Microbiol
Visualizing protein localization and characterizing gene expression activity in live
Clostridium cells is limited for lack of a real-time, highly fluorescent, oxygen-independent …

Advances in synthetic biology toolboxes paving the way for mechanistic understanding and strain engineering of gut commensal Bacteroides spp. and Clostridium spp …

Y Tan, J Liang, M Lai, S Wan, X Luo, F Li - Biotechnology Advances, 2023 - Elsevier
The gut microbiota plays a significant role in influencing human immunity, metabolism,
development, and behavior by producing a wide range of metabolites. While there is …

An Expanded Synthetic Biology Toolkit for Gene Expression Control in Acetobacteraceae

MY Teh, KH Ooi, SX Danny Teo… - ACS synthetic …, 2019 - ACS Publications
The availability of different host chassis will greatly expand the range of applications in
synthetic biology. Members of the Acetobacteraceae family of Gram-negative bacteria form …

Metabolic engineering of Clostridium autoethanogenum for ethyl acetate production from CO

JC Dykstra, J van Oort, AT Yazdi, E Vossen… - Microbial Cell …, 2022 - Springer
Background Ethyl acetate is a bulk chemical traditionally produced via energy intensive
chemical esterification. Microbial production of this compound offers promise as a more …