Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches
Pulmonary delivery of nanomedicines is very promising in lung local disease treatments
whereas several physiological barriers limit its application via the interaction with inhaled …
whereas several physiological barriers limit its application via the interaction with inhaled …
The Lord of the Lungs: The essential role of pulmonary surfactant upon inhalation of nanoparticles
The rapid development of nanotechnology is opening a huge world of promising
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …
[HTML][HTML] Application of nanotechnology in drug delivery systems for respiratory diseases
MX Luo, S Hua, QY Shang - Molecular Medicine …, 2021 - spandidos-publications.com
Respiratory disease is a common disease with a high incidence worldwide, which is a
serious threat to human health, and is considered a societal and economic burden. The …
serious threat to human health, and is considered a societal and economic burden. The …
Pivotal roles of metal oxides in the formation of environmentally persistent free radicals
Environmentally persistent free radicals (EPFRs) are emerging pollutants that can adversely
affect human health. Although the pivotal roles of metal oxides in EPFR formation have been …
affect human health. Although the pivotal roles of metal oxides in EPFR formation have been …
Microplastics and nanoplastics impair the biophysical function of pulmonary surfactant by forming heteroaggregates at the alveolar–capillary interface
X Xu, RA Goros, Z Dong, X Meng, G Li… - Environmental …, 2023 - ACS Publications
Microplastics (MPs) are ubiquitous environmental pollutants produced through the
degradation of plastic products. Nanoplastics (NPs), commonly coexisting with MPs in the …
degradation of plastic products. Nanoplastics (NPs), commonly coexisting with MPs in the …
[HTML][HTML] Engineering of pulmonary surfactant corona on inhaled nanoparticles to operate in the lung system
Exposure of inhaled nanoparticles (NPs) to the deep lung tissue results in the adsorption of
pulmonary surfactant (PSf) on the surface of NPs and the formation of a biomolecular …
pulmonary surfactant (PSf) on the surface of NPs and the formation of a biomolecular …
The emergence of nanoporous materials in lung cancer therapy
Lung cancer is one of the most common cancers, affecting more than 2.1 million people
across the globe every year. A very high occurrence and mortality rate of lung cancer have …
across the globe every year. A very high occurrence and mortality rate of lung cancer have …
[HTML][HTML] Polymeric Nanoparticles for Inhaled Vaccines
NK Al-Nemrawi, RS Darweesh, LA Al-Shriem… - Polymers, 2022 - mdpi.com
Many recent studies focus on the pulmonary delivery of vaccines as it is needle-free, safe,
and effective. Inhaled vaccines enhance systemic and mucosal immunization but still faces …
and effective. Inhaled vaccines enhance systemic and mucosal immunization but still faces …
Nano-therapeutics for the lung: state-of-the-art and future perspectives
Inhalation of aerosolized compounds is a popular, non-invasive route for the targeted
delivery of therapeutic molecules to the lung. Various types of nanoparticles have been used …
delivery of therapeutic molecules to the lung. Various types of nanoparticles have been used …
The effects of physicochemical properties of nanomaterials on their cellular uptake in vitro and in vivo
Y Liu, B Workalemahu, X Jiang - Small, 2017 - Wiley Online Library
Understanding the cellular uptake of nanomaterials (NMs) is a fundamental and critical
issue for uncovering biomedical effects of NMs and facilitating their practical applications in …
issue for uncovering biomedical effects of NMs and facilitating their practical applications in …