Small‐Molecule Inhibitors of GSK‐3: Structural Insights and Their Application to Alzheimer′ s Disease Models

T Kramer, B Schmidt, F Lo Monte - International journal of …, 2012 - Wiley Online Library
The world health organization (WHO) estimated that 18 million people are struck by
Alzheimer′ s disease (AD). The USA, France, Germany, and other countries launched …

Kinase inhibitors

Q Dong, DJ Hosfield, BR Paraselli, N Scorah… - US Patent …, 2010 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Pyrazole compounds useful as protein kinase inhibitors

R Davies, D Bebbington, R Knegtel… - US Patent …, 2008 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Pyrazole compounds useful as protein kinase inhibitors

D Bebbington, JD Charrier, J Golec, A Miller… - US Patent …, 2009 - Google Patents
2016-10-14 Assigned to VERTEX PHARMACEUTICALS INCORPORATED, VERTEX
PHARMACEUTICALS (SAN DIEGO) LLC reassignment VERTEX PHARMACEUTICALS …

Pyrazole compounds useful as protein kinase inhibitors

D Bebbington, JD Charrier, J Golec, A Miller… - US Patent …, 2009 - Google Patents
2003-07-02 Assigned to VERTEX PHARMACEUTICALS, INCORPORATED reassignment
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Pyrazolylaminopyrimidine derivatives useful as tyrosine kinase inhibitors

B Wang, T Wang - US Patent 8,114,989, 2012 - Google Patents
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Triazole compounds useful as protein kinase inhibitors

D Bebbington, R Knegtel, H Binch, JMC Golec… - US Patent …, 2011 - Google Patents
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Pyrazole compounds useful as protein kinase inhibitors

D Bebbington, H Binch, R Knegtel, JMC Golec… - US Patent …, 2010 - Google Patents
2016-10-14 Assigned to VERTEX PHARMACEUTICALS INCORPORATED, VERTEX
PHARMACEUTICALS (SAN DIEGO) LLC reassignment VERTEX PHARMACEUTICALS …

Heteroaryl compounds useful as inhibitors of gsk-3

S Harbeson, M Arnost, J Green… - US Patent App. 11/776,756, 2007 - Google Patents
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Pyrazole compounds useful as protein kinase inhibitors

R Davies, P Li - US Patent 7,473,691, 2009 - Google Patents
2003-09-10 Assigned to VERTEX PHARMACEUTICALS INCORPORATED reassignment
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