Long-term synaptic plasticity is a major cellular substrate for learning, memory, and
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …

The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …

Long-term depression (LTD) of the efficacy of synaptic transmission is now recognized as an
important mechanism for the regulation of information storage and the control of actions, as …

The cannabinoid CB1 receptors and their endogenous agonists, endocannabinoids (eCBs),
are ubiquitously distributed throughout the central nervous system (CNS), where they play a …

The endocannabinoids 2‐arachidonoylglycerol (2‐AG) and anandamide are among the
best studied lipid messengers in the brain. By activating cannabinoid receptors in the CNS …

Endocannabinoids (eCBs) are lipid-signaling molecules involved in the regulation of
numerous behaviors and physiological functions. Released by postsynaptic neurons, eCBs …

The molecular mechanisms underlying functional decline during normal brain aging are
poorly understood. Here, we identified the actin‐associated protein tropomyosin 1 (TPM1) …

The last decade has provided a wealth of experimental data on the role played by lipids
belonging to the endocannabinoid family in several facets of physiopathology of dopamine …

Research suggests that the use and abuse of marijuana can be especially harmful if it
occurs during adolescence, a period of vast developmental changes throughout the brain …

Endocannabinoids (eCBs) are lipid neuromodulators that suppress neurotransmitter
release, reduce postsynaptic excitability, activate astrocyte signaling, and control cellular …