Emodin-A natural anthraquinone derivative with diverse pharmacological activities

RB Semwal, DK Semwal, S Combrinck, A Viljoen - Phytochemistry, 2021 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone
derivative that is present in numerous globally renowned herbal medicines. It is recognised …

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

D Shrimali, MK Shanmugam, AP Kumar, J Zhang… - Cancer letters, 2013 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a natural occurring
anthraquinone derivative isolated from roots and barks of numerous plants, molds, and …

Health functions and structure–activity relationships of natural anthraquinones from plants

Y Li, JG Jiang - Food & function, 2018 - pubs.rsc.org
Anthraquinone compounds with the anthraquinone ring structure are widely found in
traditional Chinese medicines and they are attracting a lot of attention due to their good …

Naturally occurring anthraquinones: chemistry and therapeutic potential in autoimmune diabetes

SC Chien, YC Wu, ZW Chen… - … and Alternative Medicine, 2015 - Wiley Online Library
Anthraquinones are a class of aromatic compounds with a 9, 10‐dioxoanthracene core. So
far, 79 naturally occurring anthraquinones have been identified which include emodin …

Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-κB Signaling …

J Jin, YJ Fan, TV Nguyen, ZN Yu, CH Song… - International Journal of …, 2023 - mdpi.com
Fallopia japonica (Asian knotweed) is a medicinal herb traditionally used to treat
inflammation, among other conditions. However, the effects of F. japonica root extract (FJE) …

Physcion and physcion 8-O-β-glucopyranoside: A review of their pharmacology, toxicities and pharmacokinetics

Y Liu, S Chu, S Yang, Y Peng, S Ren, B Wen… - Chemico-biological …, 2019 - Elsevier
Anthraquinones constitute an important class of natural and synthetic compounds with a
broad scope of pharmacological including anti-bacterial, antioxidant, laxative, anti-tumor …

An update of anthraquinone derivatives emodin, diacerein, and catenarin in diabetes

M Martorell, N Castro, M Victoriano… - Evidence‐Based …, 2021 - Wiley Online Library
Diabetes is part of metabolic diseases and is characterized by high blood sugar levels over
a prolonged period as result of an insulin‐deficient production or an inappropriate response …

Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential

MK Apaya, TF Kuo, MT Yang, G Yang, CL Hsiao… - Pharmacological …, 2020 - Elsevier
Abstract Type 1 diabetes (T1D) is a lethal autoimmune disease afflicting as many as 10
million people worldwide. Considerable advances have been made in early diagnosis and …

Morus alba and active compound oxyresveratrol exert anti-inflammatory activity via inhibition of leukocyte migration involving MEK/ERK signaling

YC Chen, YJ Tien, CH Chen, FN Beltran… - … and Alternative Medicine, 2013 - Springer
Background Morus alba has long been used in traditional Chinese medicine to treat
inflammatory diseases; however, the scientific basis for such usage and the mechanism of …

Natural cures for type 1 diabetes: a review of phytochemicals, biological actions, and clinical potential

CLT Chang, YC Chen, HM Chen… - Current Medicinal …, 2013 - ingentaconnect.com
Autoimmune diseases are the third largest category of illness in the industrialized world,
following cardiovascular diseases and cancers. Among them, type 1 diabetes, also named …