Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …

Adaptive laboratory evolution (ALE) is an innovative approach for the generation of evolved
microbial strains with desired characteristics, by implementing the rules of natural selection …

Lignin is one of the most abundant renewable resources on earth and is readily produced as
a sidestream during biomass fractioning. So far, these large quantities of lignin have been …

Adaptive laboratory evolution is a frequent method in biological studies to gain insights into
the basic mechanisms of molecular evolution and adaptive changes that accumulate in …

Evolutionary changes in organismal traits may occur either gradually or suddenly. However,
until recently, there has been little direct information about how phenotypic changes are …

In experimental evolution, laboratory-controlled conditions select for the adaptation of
species, which can be monitored in real time. Despite the current popularity of such …

During microbial production of solvent-like compounds, such as advanced biofuels and bulk
chemicals, accumulation of the final product can negatively impact the cultivation of the host …

Background Mutations that alter chromosomal structure play critical roles in evolution and
disease, including in the origin of new lifestyles and pathogenic traits in microbes. Large …

This work presents a detailed analysis of the production design and economics of the
cellulosic isobutanol conversion processes and compares cellulosic isobutanol with …