Evidence that nanoscale surface properties stimulate and guide various molecular and
biological processes at the implant/tissue interface is fostering a new trend in designing …

Today, surgical intervention remains the mainstay of treatment to intervene upon a multitude
of skeletal deficits and defects attributable to congenital malformations, oncologic resection …

Human mesenchymal stem cells (hMSCs) differentiate down an osteogenic pathway with
appropriate mechanical and/or chemical stimuli. This study describes the successful culture …

The role of angiogenesis during mechanically induced bone formation is incompletely
understood. The relationship between the mechanical environment, angiogenesis, and …

Implant loading can create micromotion at the bone–implant interface. The interfacial strain
associated with implant micromotion could contribute to regulating the tissue healing …

Nanocomposite biomaterials are extensively investigated for cell and tissue engineering
applications due their unique physical, chemical and biological characteristics. Here, we …

We have shown that the uniaxial cyclic tensile strain of magnitude 10% promotes and
enhances osteogenesis of human mesenchymal stem cells (hMSC) and human adipose …

We investigated the effects of two types of cyclic tensile strain, continuous and rest inserted,
on osteogenic differentiation of human adipose-derived adult stem cells (hASCs). The …

BACKGROUND: Distraction osteogenesis is a valuable clinical tool; however the molecular
mechanisms governing successful distraction remain unknown. We have used a uniaxial in …

This review aims to highlight the current and significant work in the use of adipose-derived
stem cells (ASC) in functional bone tissue engineering framed through the bone …