Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis
Doxorubicin is an effective anti-neoplastic agent; the reported toxicities of DOX limit its use.
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …
Caffeic acid mitigates aflatoxin B1‐mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and …
Abstract Aflatoxin B1 (AFB1) is a toxic metabolite of public health concern. The present study
investigates the protective effects of caffeic acid (CA) against AFB1‐induced oxidative stress …
investigates the protective effects of caffeic acid (CA) against AFB1‐induced oxidative stress …
Co-administration of Luteolin mitigated toxicity in rats' lungs associated with doxorubicin treatment
Doxorubicin (DOX), is a drug against lung malignancies with undesirable side effect
including oxidative, inflammatory and apoptotic effects. Luteolin (LUT), present in fruits and …
including oxidative, inflammatory and apoptotic effects. Luteolin (LUT), present in fruits and …
[HTML][HTML] Nephroprotective effects of Acacia Senegal against aflatoxicosis via targeting inflammatory and apoptotic signaling pathways
Abstract Aflatoxin B 1 (AFB1) is a common environmental pollutant that poses a major
hazard to both humans and animals. Acacia senegal (Gum) is well-known for having …
hazard to both humans and animals. Acacia senegal (Gum) is well-known for having …
3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of …
We examined the effect of 3-Indolepropionic acid (3-IPA), an antioxidant on the
organophosphorus pesticide chlorpyrifos (CPF)-induced reproductive toxicity in rats. The …
organophosphorus pesticide chlorpyrifos (CPF)-induced reproductive toxicity in rats. The …
The modulatory effect of taurine on benzo (a) pyrene-induced hepatorenal toxicity
SE Owumi, G Adeniyi, AK Oyelere - Toxicology research, 2021 - academic.oup.com
Toxicities linked with Benzo (a) pyrene B [a] P exposure, particularly in liver and kidney have
been reported in both animals and humans. Taurine (2-aminoethane sulfonic acid) is an …
been reported in both animals and humans. Taurine (2-aminoethane sulfonic acid) is an …
[HTML][HTML] Morin provides therapeutic effect by attenuating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and oxidative DNA …
Objective (s): In the present study, it was evaluated whether morin has a protective effect on
testicular toxicity caused by ifosfamide (IFOS), which is used in the treatment of various …
testicular toxicity caused by ifosfamide (IFOS), which is used in the treatment of various …
Biochemical and histological alterations of doxorubicin‐induced neurotoxicity in rats: protective role of luteolin
IO Imosemi, SE Owumi… - Journal of Biochemical and …, 2022 - Wiley Online Library
Doxorubicin (DOX) is a chemotherapeutic drug used in the treatment of various cancer
types. DOX toxic side effects include neuronopathy and memory deficits. We investigated the …
types. DOX toxic side effects include neuronopathy and memory deficits. We investigated the …
Inhibition of human glutathione transferase by catechin and gossypol: comparative structural analysis by kinetic properties, molecular docking and their efficacy on the …
RA Guneidy, ER Zaki, NS Saleh… - The Journal of …, 2024 - academic.oup.com
Glutathione transferase Pi (GSTP1) expression is increased in many cancer types and is
associated with multidrug resistance and apoptosis inhibition. Inhibitors of GSTP1-1 have …
associated with multidrug resistance and apoptosis inhibition. Inhibitors of GSTP1-1 have …
Inflammatory modulation of miR-155 inhibits doxorubicin-induced testicular dysfunction via SIRT1/FOXO1 pathway: insight into the role of acacetin and Bacillus cereus …
HM Anwar, SR Hamad, GEM Salem… - Applied Biochemistry …, 2022 - Springer
Doxorubicin (DOX) is a chemotherapeutic agent that can disrupt testicular function leading
to male infertility. This study examined the protective role of natural flavone, acacetin (ACA) …
to male infertility. This study examined the protective role of natural flavone, acacetin (ACA) …