Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

RD Klein, SJ Hultgren - Nature Reviews Microbiology, 2020 - nature.com
Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …

Uropathogen and host responses in pyelonephritis

L Schwartz, J de Dios Ruiz-Rosado… - Nature Reviews …, 2023 - nature.com
Urinary tract infections (UTIs) are among the most common bacterial infections seen in
clinical practice. The ascent of UTI-causing pathogens to the kidneys results in …

Association between caseload surge and COVID-19 survival in 558 US hospitals, March to August 2020

SS Kadri, J Sun, A Lawandi, JR Strich… - Annals of Internal …, 2021 - acpjournals.org
Background: Several US hospitals had surges in COVID-19 caseload, but their effect on
COVID-19 survival rates remains unclear, especially independent of temporal changes in …

Assessment of health care exposures and outcomes in adult patients with sepsis and septic shock

K Fay, MRP Sapiano, R Gokhale, R Dantes… - JAMA network …, 2020 - jamanetwork.com
Importance Current information on the characteristics of patients who develop sepsis may
help in identifying opportunities to improve outcomes. Most recent studies of sepsis …

Evaluating the costs and outcomes of hospital nursing resources: a matched cohort study of patients with common medical conditions

KB Lasater, MD McHugh, PR Rosenbaum… - Journal of General …, 2021 - Springer
Background Nursing resources, such as staffing ratios and skill mix, vary across hospitals.
Better nursing resources have been linked to better patient outcomes but are assumed to …

SSP: Early prediction of sepsis using fully connected LSTM-CNN model

A Rafiei, A Rezaee, F Hajati, S Gheisari… - Computers in biology and …, 2021 - Elsevier
Background Sepsis is a life-threatening condition that occurs due to the body's reaction to
infections, and it is a leading cause of morbidity and mortality in hospitals. Early prediction of …

[HTML][HTML] Guidelines for antibiotic prescription in intensive care unit

GC Khilnani, K Zirpe, V Hadda, Y Mehta… - Indian journal of …, 2019 - ncbi.nlm.nih.gov
How to cite this article: Khilnani GC, Zirpe K, Hadda V, Mehta Y, Madan K, Kulkarni A,
Mohan A, Dixit S, Guleria R, Bhattacharya P. Guidelines for Antibiotic Prescription in …

Safety and immunogenicity of an adjuvanted Escherichia coli adhesin vaccine in healthy women with and without histories of recurrent urinary tract infections: results …

GR Eldridge, H Hughey, L Rosenberger… - Human vaccines & …, 2021 - Taylor & Francis
Antibiotic resistance among gram-negative bacteria continues to rise globally at an alarming
rate. New vaccines that prevent bacterial infections and reduce antibiotic use could provide …

Predictive phage therapy for Escherichia coli urinary tract infections: Cocktail selection for therapy based on machine learning models

M Keith, A Park de la Torriente… - Proceedings of the …, 2024 - National Acad Sciences
This study supports the development of predictive bacteriophage (phage) therapy: the
concept of phage cocktail selection to treat a bacterial infection based on machine learning …

Comparative prognostic accuracy of sepsis scores for hospital mortality in adults with suspected infection in non-ICU and ICU at an academic public hospital

CP Kovach, GS Fletcher, KE Rudd, RM Grant… - PloS one, 2019 - journals.plos.org
Background Sepsis is a global healthcare challenge and reliable tools are needed to
identify patients and stratify their risk. Here we compare the prognostic accuracy of the …