New case of pharmaceutical solid-state forms: Several novel solvates/polymorphs of nilotinib and their phase transformation controls

X Shi, Q Chen, Y Deng, X Xing, C Wang… - Crystal Growth & …, 2022 - ACS Publications
Nilotinib as a type of anticancer drug was designed for the treatment of chronic myeloid
leukemia that is resistant to imatinib. Presently, very few studies of nilotinib polymorphs have …

Evaluation of topical anti-inflammatory effects of a gel formulation with Plantago lanceolata, Achillea millefolium, Aesculus hippocastanum and Taxodium distichum

A Zanfirescu, G Nitulescu, G Stancov… - Scientia …, 2020 - mdpi.com
Medicinal plants hold a significant place as alternative treatments available for inflammatory
diseases, with many phytoconstituents being frequently tested in vitro for their biological …

[PDF][PDF] 3, 3′-(Phenylmethylene) bis (1-ethyl-3, 4-dihydro-1H-2, 1-benzothiazine-2, 2, 4-trione): single-crystal X-ray diffraction study, quantum-chemical calculations …

MO Shyshkina, DA Lega, LM Shemchuk… - Acta …, 2023 - journals.iucr.org
The title compound, C27H26N2O6S2, possesses potential antimicrobial, analgesic, and anti-
inflammatory activity. This compound has three tautomeric forms, which relative energies …

In-depth investigation of analgesic activity of N-(4-methoxybenzyl)-4-methyl-2.2-dioxo-1H-2 λ6. 1-benzothiazine-3-carboxamide derivate on different models of pain …

OV Malchenko - Biomedical and biosocial anthropology, 2021 - bba-journal.com
Abstract Among N-(4-methoxybenzyl)-4-methyl-2.2-dioxo-1H-2 λ 6. 1-benzothiazine-3-
carboxamide derivates, the compound methoxybenzyl-amide derivative 4-methyl-2.2-dioxo …

Investigation of pharmacokinetics of N-(4-trifluoromethylphenyl)-4-methyl-2.2-dioxo-1H-2λ6. 1-benzothiazine-3-carboxamide various crystalline modifications in vivo

PS Bondarenko, NI Voloshchuk… - Biomedical and …, 2020 - bba-journal.com
The phenomenon of polymorphism, inherent in many biologically active substances,
including drugs, is an extremely serious problem that requires close attention and …

[PDF][PDF] Formulation and Evaluation of Herbal (Nelumbo Nucifera) Anti-Inflammatory Gel

P Keshri, S Kumar, P Tiwari - ijpdd.org
The gel has the safest, easily applicable and most effective due to its directly applicable to
the infected part of the skin with minimal adverse effect. This research explores the …

Investigation of anti-inflammatory and antipyretic activity of polymorphic modification of n-(trifluoromethylphenyl)-4-hydroxy-2, 2-dioxo-1h-2λ6, 1-benzothiazine-3 …

PS Bondarenko, NІ Voloshchuk - Reports of Vinnytsia …, 2021 - reports-vnmedical.com.ua
Annotation. Polymorphism among biologically active substances is an extremely important
factor that modifies the therapeutic properties of pharmaceutical substances and dosage …