Mesenchymal stem cells (MSCs) represent an attractive cell type for research and therapy
due to their ability to proliferate, differentiate, modulate immune reactions, and secrete …

Liver cirrhosis is a major cause of mortality and a common end of various progressive liver
diseases. Since the effective treatment is currently limited to liver transplantation, stem cell …

The existing mismatch between the great demand for liver transplants and the number of
available donor organs highlights the urgent need for alternative therapeutic strategies in …

Recent technological developments in biomedicine have facilitated the generation of data
on the anatomical, physiological and molecular level for individual patients and thus …

Establishing an effective method to improve stem cell differentiation is crucial in stem cell
transplantation. Here we aimed to explore whether and how sodium butyrate (NaB) induces …

Tens of millions of patients are affected by liver disease worldwide. Many of these patients
can benefit from cell therapy involving living metabolically active cells, either by treatment of …

摘要目的: 研究开发一种简易, 快速在体外使多能诱导干细胞(induced pluripotent stem cells,
iPSCs) 定向分化为功能性肝样细胞的培养方法. 方法: 根据正常肝细胞在体内的发育规律 …

Decellularized tissues (DETs) have been attracting great attention as scaffolds for tissue-
engineering approaches. Recently, some studies have reported that decellularized liver …

Hepatocyte transplantation is considered to be a promising therapy for patients with liver
diseases. Induced pluripotent stem cells (iPSCs) provide an unlimited source for the …

The scope of this review is to revise recent advances of the cell-based therapies of liver
diseases with an emphasis on cell donor's and patient's age. Regenerative medicine with …