There are numerous proteases of pathogenic organisms that are currently targeted for
therapeutic intervention along with many that are seen as potential drug targets. This review …

The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

Human transmembrane serine protease 2 (TMPRSS2) is an important member of the type 2
transmembrane serine protease (TTSP) family with significant therapeutic markings. The …

Extensive research into the therapeutics of asthma has yielded numerous effective
interventions over the past few decades. However, adverse effects and ineffectiveness of …

Malaria causes about half a million deaths annually, with Plasmodium falciparum being
responsible for 90% of all the cases. Recent reports on artemisinin resistance in Southeast …

Metabolic enzymes have been known to carry out a variety of functions besides their normal
housekeeping roles known as “moonlighting functions.” These functionalities arise from …

Screening of the GSK corporate collection, some 1.9 million compounds, against
Plasmodium falciparum (Pf), revealed almost 14000 active hits that are now known as the …

Background Falcipains are major cysteine proteases of Plasmodium falciparum involved in
haemoglobin degradation and remain attractive anti-malarial drug targets. Several inhibitors …

There is an unmet need to unearth alternative treatment options for malaria, wherein this
quest is more pressing in recent times due to high morbidity and mortality data arising mostly …

" A book is like a garden carried in the pocket."–Chinese proverb This Chinese proverb
simply means: Reading helps strengthen one's intellect, which correlates with the feeling …