Rheumatoid arthritis (RA) is currently diagnosed and treated when an individual presents
with signs and symptoms of inflammatory arthritis (IA) as well as other features, such as …

Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …

Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the
world population and is a significant cause of worldwide disability. Though prior studies …

In rheumatoid arthritis (RA), immunological triggers at mucosal sites, such as the gut
microbiota, may promote autoimmunity that affects joints. Here, we used discovery-based …

The understanding of the pathogenesis and optimal therapeutics for rheumatoid arthritis
(RA) has advanced remarkably over the last decade. This review highlights these key …

Objective The presence of anti-citrullinated protein antibodies (ACPA) and IgM-rheumatoid
factor (IgM-RF) years before the clinical diagnosis of rheumatoid arthritis (RA) suggests they …

Rheumatoid arthritis (RA) is a chronic inflammatory syndrome with a strong autoimmune
component. The autoantigens in RA are neither tissue nor organ‐specific, but comprise a …

Objective To examine the relationship of Porphyromonas gingivalis to the presence of
autoantibodies in individuals at risk of rheumatoid arthritis (RA). Methods Study participants …

Increasingly, assays for the detection of anti-citrullinated peptide antibodies (ACPA) are
used in RA diagnosis. This review summarizes the biologic basis and development of ACPA …