Cytokines are major drivers of autoimmunity, and biologic agents targeting cytokines have
revolutionized the treatment of immune-mediated diseases. Despite the effectiveness of …

Abstract Signal Transducers and Activators of Transcription (STATs) comprise an important
class of transcription factors that have been implicated in a wide variety of essential cellular …

Atherosclerosis is the main pathological basis of ischemic cardiovascular and
cerebrovascular diseases and has attracted more attention in recent years. Multiple studies …

Peripheral blood of cancer patients “physiologically” presents cells and cellular components
deriving from primary or metastatic sites, including circulating tumor cells (CTCs), circulating …

Background: Biogenic silver nanoparticles (AgNPs) have wider range of biomedical
applications. The present work synthesized Tp-AgNPs using mycelial extract of endophytic …

Signal transducer and activator of transcription 3 (STAT3), a member of the STAT protein
family, can be phosphorylated by receptor-associated Janus kinases (JAKs) in response to …

The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …

STATs constitute a large family of transcription activators and transducers of signals that
have an important role in many cell functions as regulation of proliferation and differentiation …

Green nanotechnology is currently a very crucial and indispensable technology for handling
diverse problems regarding the living planet. The concoction of reactive oxygen species …

Thymoquinone (TQ), isolated almost fifty years ago, is the main bioactive constituent of black
seed essential oil extracted from the seed of Nigella sativa. TQ has been shown to have …