The Role of Porphyromonas gingivalis Outer Membrane Vesicles in Periodontal Disease and Related Systemic Diseases

Z Zhang, D Liu, S Liu, S Zhang, Y Pan - Frontiers in cellular and …, 2021 - frontiersin.org
Periodontal disease is a chronic infectious disease associated with a variety of bacteria,
which can cause damage to the periodontal support structure and affect a variety of systemic …

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

C Schwechheimer, MJ Kuehn - Nature reviews microbiology, 2015 - nature.com
Outer-membrane vesicles (OMVs) are spherical buds of the outer membrane filled with
periplasmic content and are commonly produced by Gram-negative bacteria. The production …

Outer membrane vesicles: biogenesis, functions, and issues

R Juodeikis, SR Carding - Microbiology and Molecular Biology …, 2022 - Am Soc Microbiol
This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial
extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the …

Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

Molecular strategies underlying Porphyromonas gingivalis virulence

IL Silva, E Cascales - Journal of Molecular Biology, 2021 - Elsevier
The anaerobic Gram-negative bacterium Porphyromonas gingivalis is considered the
keystone of periodontitis diseases, a set of inflammatory conditions that affects the tissues …

Shared and distinct mechanisms of iron acquisition by bacterial and fungal pathogens of humans

M Caza, JW Kronstad - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
Iron is the most abundant transition metal in the human body and its bioavailability is
stringently controlled. In particular, iron is tightly bound to host proteins such as transferrin to …

Porphyromonas gingivalis Outer Membrane Vesicles Exclusively Contain Outer Membrane and Periplasmic Proteins and Carry a Cargo Enriched with Virulence …

PD Veith, YY Chen, DG Gorasia, D Chen… - Journal of proteome …, 2014 - ACS Publications
Porphyromonas gingivalis, a keystone pathogen associated with chronic periodontitis,
produces outer membrane vesicles (OMVs) that carry a cargo of virulence factors. In this …

Iron acquisition strategies of bacterial pathogens

JR Sheldon, HA Laakso… - Virulence Mechanisms of …, 2016 - Wiley Online Library
Iron is essential to nearly all life forms on Earth, required for the proper function of enzymes
involved in, for example, respiration, photosynthesis, the tricarboxylic acid cycle, nitrogen …

Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis

AC Darby, SD Armstrong, GS Bah, G Kaur… - Genome …, 2012 - genome.cshlp.org
The α-proteobacterium Wolbachia is probably the most prevalent, vertically transmitted
symbiont on Earth. In contrast with its wide distribution in arthropods, Wolbachia is restricted …

Spheres of influence: Porphyromonas gingivalis outer membrane vesicles

MJ Gui, SG Dashper, N Slakeski… - Molecular oral …, 2016 - Wiley Online Library
Outer membrane vesicles (OMV s) are asymmetrical single bilayer membranous
nanostructures produced by Gram‐negative bacteria important for bacterial interaction with …