Novel insights on pyoverdine: from biosynthesis to biotechnological application

F Dell'Anno, GA Vitale, C Buonocore, L Vitale… - International Journal of …, 2022 - mdpi.com
Pyoverdines (PVDs) are a class of siderophores produced mostly by members of the genus
Pseudomonas. Their primary function is to accumulate, mobilize, and transport iron …

Adding siderophores: a new strategy to reduce greenhouse gas emissions in composting

L Jiang, Y Zhao, Y Yao, J Lou, Y Zhao, B Hu - Bioresource Technology, 2023 - Elsevier
Microbial community is the primary driver causing the greenhouse gas emissions in
composting. Thus, regulating the microbial communities is a strategy to reduce them. Here …

Pseudomonas aeruginosa FpvB is a high-affinity transporter for xenosiderophores ferrichrome and ferrioxamine B

DCK Chan, LL Burrows - Mbio, 2023 - Am Soc Microbiol
Iron is essential for many biological functions in bacteria, but its poor solubility is a limiting
factor for growth. Bacteria produce siderophores, soluble natural products that bind iron with …

Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens

V Vollenweider, K Rehm, C Chepkirui… - eLife, 2024 - elifesciences.org
The global rise of antibiotic resistance calls for new drugs against bacterial pathogens. A
common approach is to search for natural compounds deployed by microbes to inhibit …

Experimental evolution of yeast shows that public-goods upregulation can evolve despite challenges from exploitative non-producers

RJ Lindsay, PJ Holder, M Hewlett, I Gudelj - Nature Communications, 2024 - nature.com
Microbial secretions, such as metabolic enzymes, are often considered to be cooperative
public goods as they are costly to produce but can be exploited by others. They create …

Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

S Gu, Y Shao, K Rehm, L Bigler, D Zhang, R He, R Xu… - Elife, 2024 - elifesciences.org
Microbial secondary metabolites are a rich source for pharmaceutical discoveries and play
crucial ecological functions. While tools exist to identify secondary metabolite clusters in …

Resazurin-based high-throughput screening method for the discovery of dietary phytochemicals to target microbial transformation of l-carnitine into trimethylamine, a …

C Simó, T Fornari, MR García-Risco, A Peña-Cearra… - Food & Function, 2022 - pubs.rsc.org
Nowadays, there is great interest in the discovery of food compounds that might inhibit gut
microbial TMA production from its methylamine precursors. In this work, an innovative novel …

Type IV secretion system effector sabotages multiple defense systems in a competing bacterium

B Wang, F Xu, Z Zhang, D Shen, L Wang… - The ISME …, 2024 - academic.oup.com
Effector proteins secreted by bacteria that infect mammalian and plant cells often subdue
eukaryotic host cell defenses by simultaneously affecting multiple targets. However …

From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

S Gu, Y Shao, K Rehm, L Bigler, D Zhang, R He, R Xu… - bioRxiv, 2023 - biorxiv.org
Microbial secondary metabolites have long been recognized as a rich source for
pharmaceutical compound discovery and to have crucial ecological functions. However, the …

Local adaptation, geographical distance and phylogenetic relatedness: Assessing the drivers of siderophore‐mediated social interactions in natural bacterial …

E Butaitė, J Kramer, R Kümmerli - Journal of Evolutionary …, 2021 - academic.oup.com
In heterogenous, spatially structured habitats, individuals within populations can become
adapted to the prevailing conditions in their local environment. Such local adaptation has …