Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive
malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of …

The standard of care for isocitrate dehydrogenase (IDH)-wildtype glioblastoma (GBM) is
maximal resection followed by chemotherapy and radiation. Studies investigating the …

Purpose To synthesize the evidence on the impact on progression-free survival (PFS) and
overall survival (OS) of supramaximal resection (SMR) over gross total resection (GTR) in …

After recent updates to the World Health Organization pathological criteria for diagnosing
and grading diffuse gliomas, all major North American and European neuro-oncology …

Background Glioblastoma (GBM), one of the most lethal tumors, exhibits a highly infiltrative
phenotype. Here, we identified transcription factors (TFs) that collectively modulate invasion …

Objective To study the role of laser interstitial thermal therapy in recurrent glioblastoma and
to assess its effect in the overall survival and in progression-free survival. Methods A …

Simple Summary Glioblastoma tumor cells are frequently found in areas distant from
conventional imaging abnormalities. These cells are thought to play a role in tumor …

Purpose Extent of resection remains a paramount prognostic factor for long-term outcomes
for glioblastoma. As such, supramaximal resection or anatomic lobectomy have been offered …

Cellular composition and molecular signatures of the glioma core compared with infiltrative
margins are different, and it is well known that the tumor edge is enriched in microglia. In this …

Current standard of care for glioblastoma is surgical resection followed by temozolomide
chemotherapy and radiation. Recent studies have demonstrated that> 95% extent of …