CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

Migration of polymorphonuclear neutrophil leukocytes (PMN) into the mammary gland
provide the first line of defense against invading mastitis pathogens. Bacteria release potent …

Over the past decade, our understanding of apoptosis, or programmed cell death, has
increased greatly, with the identification of some of the major components of the apoptotic …

Human neutrophils constitutively undergo apoptosis and this process is critical for the
resolution of inflammation. Whilst neutrophil apoptosis can be modulated by a wide variety …

Neutrophils are constantly produced in large numbers in the bone marrow, and the same
numbers of cells need to die within a defined time period in order to keep cellular …

The isoforms of the PKC family are activated in response to mitogenic stimuli, to
inflammatory stimuli, and to stress and play important roles in a variety of cellular functions …

Neutrophil constitutive death is a critical cellular process for modulating neutrophil number
and function, and it plays an essential role in neutrophil homeostasis and the resolution of …

Macrophages are the major target cell population of the obligate intracellular parasites
Leishmania. Although polymorphonuclear neutrophil granulocytes (PMN) are able to …

The Rho-GDP guanine nucleotide dissociation inhibitor (GDI) complexes with the GDP-
bound form of Rho and inhibits its activation. We investigated the role of protein kinase C …

We have shown previously that protein kinase Cδ (PKCδ) is required for mitochondrial‐
dependent apoptosis. Here we show that PKCδ is imported into the nucleus of etoposide …