Simple Summary Glutathione peroxidase 1 (GPX1), as one of the most important antioxidant
enzymes, maintains cellular redox balance by regulating reactive oxygen species levels. In …

Elevated mitochondrial matrix superoxide and/or hydrogen peroxide concentrations drive a
wide range of physiological responses and pathologies. Concentrations of superoxide and …

The relevance of reactive oxygen species (ROS) production relies on the dual role shown by
these molecules in aerobes. ROS are known to modulate several physiological phenomena …

Type 2 diabetes mellitus (T2DM) is a metabolic disorder resulting from oxidative stress (OS),
the root cause of insulin resistance, β-cell dysfunction, and impaired glucose tolerance …

Reactive oxygen species-related damage plays a critical role in carcinogenesis. Glutathione
peroxidase 1 (GPX1) and mitochondrial superoxide dismutase (MnSOD) are two key …

Objective To evaluate the relationship between manganese superoxide dismutase (MnSOD)
Ile58Thr, catalase (CAT) C‐262 T and myeloperoxidase (MPO) G‐463 A gene …

Background: Oxidative stress plays an important role in the pathogenesis of polycystic ovary
syndrome (PCOS). Glutathione peroxidase 1 (GPx1) and catalase (CAT) are the major …

Over the past decades, several studies have shown that tumor-related somatic and germline
alterations predicts tumor prognosis, drug response and toxicity. Latin American populations …

Background: The correlation between superoxide dismutase 2 (SOD2) V16A variant and
urological cancer susceptibility has been widely studied, however, with divergent results …

Purpose NRF2 transcription factor is involved in modulation of various antioxidant and
metabolic genes and, therefore, may modulate anti-carcinogenic potential. Association …