The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

[HTML][HTML] Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease

F Åberg, CD Byrne, CJ Pirola, V Männistö… - Journal of …, 2023 - Elsevier
Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Multiomics study of nonalcoholic fatty liver disease

G Sveinbjornsson, MO Ulfarsson, RB Thorolfsdottir… - Nature …, 2022 - nature.com
Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed
a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and …

Oxidative stress in liver pathophysiology and disease

A Allameh, R Niayesh-Mehr, A Aliarab, G Sebastiani… - Antioxidants, 2023 - mdpi.com
The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Insights into nonalcoholic fatty-liver disease heterogeneity

M Arrese, JP Arab, F Barrera… - Seminars in liver …, 2021 - thieme-connect.com
The acronym nonalcoholic fatty-liver disease (NAFLD) groups a heterogeneous patient
population. Although in many patients the primary driver is metabolic dysfunction, a complex …

[PDF][PDF] Alcohol-associated liver disease mortality increased from 2017 to 2020 and accelerated during the COVID-19 pandemic

S Deutsch-Link, Y Jiang, AF Peery, AS Barritt… - Clinical …, 2022 - Elsevier
Alcohol consumption has risen substantially in the United States (US) in the past two
decades. 1, 2 Alcohol-associated liver disease (ALD) represents a greater inpatient financial …

Diet and exercise in NAFLD/NASH: beyond the obvious

G Semmler, C Datz, T Reiberger… - Liver International, 2021 - Wiley Online Library
Lifestyle represents the most relevant factor for non‐alcoholic fatty liver disease (NAFLD) as
the hepatic manifestation of the metabolic syndrome. Although a tremendous body of clinical …

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality

LA van Kleef, RJ de Knegt, WP Brouwer - Hepatology, 2023 - journals.lww.com
Metabolic dysfunction‐associated fatty liver disease and exc... : Hepatology Metabolic
dysfunction‐associated fatty liver disease and excessive alcohol consumption are both …

Gut–Liver axis and non-alcoholic fatty liver disease: A vicious circle of dysfunctions orchestrated by the gut microbiome

S Pezzino, M Sofia, G Faletra, C Mazzone, G Litrico… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is a widespread disease
associated with metabolic disorders, such as obesity. In recent years, there has been …

PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date

A Cherubini, E Casirati, M Tomasi… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction An interaction between metabolic triggers and inherited predisposition
underpins the development and progression of non alcoholic fatty liver disease (NAFLD) …