Isolation, cultivation, and characterization of human mesenchymal stem cells

D Mushahary, A Spittler, C Kasper, V Weber… - Cytometry Part …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSC) exhibit a high self‐renewal capacity, multilineage
differentiation potential and immunomodulatory properties. This set of exceptional features …

Biology and therapeutic potential of mesenchymal stem cell‐derived exosomes

Z Xunian, R Kalluri - Cancer Science, 2020 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent stromal cells with the potential to
differentiate into several cell types. MSC‐based therapy has emerged as a promising …

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in …

P Godoy, NJ Hewitt, U Albrecht, ME Andersen… - Archives of …, 2013 - Springer
This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA

A Conigliaro, V Costa, A Lo Dico, L Saieva, S Buccheri… - Molecular cancer, 2015 - Springer
Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC),
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …

[HTML][HTML] Charge-based precipitation of extracellular vesicles

MC Deregibus, F Figliolini… - International …, 2016 - spandidos-publications.com
Vesicular-mediated communication between cells appears critical in many biological
processes. Extracellular vesicles (EVs) released from healthy and diseased cells are …

The therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles

T Katsuda, N Kosaka, F Takeshita, T Ochiya - Proteomics, 2013 - Wiley Online Library
Extracellular vesicles (EV s), membrane vesicles that are secreted by a variety of
mammalian cell types, have been shown to play an important role in intercellular …

Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy

C Grange, S Tritta, M Tapparo, M Cedrino, C Tetta… - Scientific reports, 2019 - nature.com
Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have
been shown to reprogram injured cells by activating regenerative processes. We herein …

2D Ti3C2TxMXene couples electrical stimulation to promote proliferation and neural differentiation of neural stem cells

R Guo, M Xiao, W Zhao, S Zhou, Y Hu, M Liao, S Wang… - Acta Biomaterialia, 2022 - Elsevier
Preclinical studies involving stem cells require efficient physiochemical regulations on the
fate of such cells. Because of their unique planar structure, metallic conductivity, and flexible …

[HTML][HTML] Significance of CD90+ cancer stem cells in human liver cancer

ZF Yang, DW Ho, MN Ng, CK Lau, WC Yu, P Ngai… - Cancer cell, 2008 - cell.com
This study characterized cancer stem cells (CSCs) in hepatocellular carcinoma (HCC) cell
lines, tumor specimens, and blood samples. The CD90+ cells, but not the CD90− cells, from …

Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs

F Collino, MC Deregibus, S Bruno, L Sterpone… - PloS one, 2010 - journals.plos.org
Background Cell-derived microvesicles (MVs) have been described as a new mechanism of
cell-to-cell communication. MVs after internalization within target cells may deliver genetic …