[HTML][HTML] Targeting selective autophagy and beyond: From underlying mechanisms to potential therapies
W Ma, Y Lu, X Jin, N Lin, L Zhang, Y Song - Journal of Advanced Research, 2024 - Elsevier
Background Autophagy is an evolutionarily conserved turnover process for intracellular
substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) …
substances in eukaryotes, relying on lysosomal (in animals) or vacuolar (in yeast and plants) …
[HTML][HTML] Targeting Autophagy for Acetaminophen-Induced Liver Injury: An Update
Acetaminophen (APAP) overdose can induce hepatocyte necrosis and acute liver failure in
experimental rodents and humans. APAP is mainly metabolized via hepatic cytochrome …
experimental rodents and humans. APAP is mainly metabolized via hepatic cytochrome …
A Review of the Role of Caveolin-1 in Acetaminophen-Induced Liver Injury
W Jiang, J Wang, J Wang, X Chen, Z Fang, C Hu - Pharmacology, 2024 - karger.com
Background: Acetaminophen (APAP) is commonly used as an antipyretic and analgesic
agent. Excessive APAP can induce liver toxicity, known as APAP-induced liver injury (ALI) …
agent. Excessive APAP can induce liver toxicity, known as APAP-induced liver injury (ALI) …
Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway
As defined by the N-degron pathway, single N-terminal (Nt) amino acids can function as N-
degrons that induce the degradation of proteins and other biological materials. Central to …
degrons that induce the degradation of proteins and other biological materials. Central to …
Effect of exogenous IGF-1 administration on acetaminophen toxicity induced liver injury: IGF-1 protects against liver injury
For liver toxicity, there is no clear protective drug till date. Here, we investigated the
protective effects of insulin-like growth factor 1 (IGF-1) on acetaminophen (APAP)-induced …
protective effects of insulin-like growth factor 1 (IGF-1) on acetaminophen (APAP)-induced …