The cadherin superfamily: diversity in form and function

BD Angst, C Marcozzi, AI Magee - Journal of cell science, 2001 - journals.biologists.com
Over recent years cadherins have emerged as a growing superfamily of molecules, and a
complex picture of their structure and their biological functions is becoming apparent …

Adiponectin signaling in the liver

TP Combs, EB Marliss - Reviews in Endocrine and Metabolic Disorders, 2014 - Springer
High glucose production contributes to fed and fasted hyperglycemia in Type 1 Diabetes
(T1D) and Type 2 Diabetes (T2D). The breakdown of the adiponectin signaling pathway in …

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

T Yeung, PC Georges, LA Flanagan… - Cell motility and the …, 2005 - Wiley Online Library
The morphology and cytoskeletal structure of fibroblasts, endothelial cells, and neutrophils
are documented for cells cultured on surfaces with stiffness ranging from 2 to 55,000 Pa that …

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin

C Hug, J Wang, NS Ahmad, JS Bogan… - Proceedings of the …, 2004 - National Acad Sciences
Acrp30/adiponectin is reduced in the serum of obese and diabetic individuals, and the
genetic locus of adiponectin is linked to the metabolic syndrome. Recombinant adiponectin …

T-cadherin is essential for adiponectin-mediated revascularization

JL Parker-Duffen, K Nakamura, M Silver… - Journal of Biological …, 2013 - ASBMB
Adipose tissue secretes protein factors that have systemic actions on cardiovascular tissues.
Previous studies have shown that ablation of the adipocyte-secreted protein adiponectin …

Adiponectin association with T‐cadherin protects against neointima proliferation and atherosclerosis

Y Fujishima, N Maeda, K Matsuda… - The FASEB …, 2017 - Wiley Online Library
Adiponectin, an adipocyte‐derived protein abundant in the circulation, is thought to be
protective against atherosclerosis. However, it is not fully understood how the association of …

The cadherin–catenin complex as a focal point of cell adhesion and signalling: new insights from three‐dimensional structures

JM Gooding, KL Yap, M Ikura - Bioessays, 2004 - Wiley Online Library
Cadherins are a large family of single‐pass transmembrane proteins principally involved in
Ca2+‐dependent homotypic cell adhesion. The cadherin molecules comprise three …

Structure and functions of classical cadherins

DB Ivanov, MP Philippova, VA Tkachuk - Biochemistry (Moscow), 2001 - Springer
Cadherins are a family of membrane receptors that mediate calcium-dependent homophilic
cell–cell adhesion. Cadherins play a key role in the regulation of organ and tissue …

Expression of cell adhesion molecule T-cadherin in the human vasculature

D Ivanov, M Philippova, J Antropova… - Histochemistry and cell …, 2001 - Springer
Alterations in expression of surface adhesion molecules on resident vascular and blood-
derived cells play a fundamental role in the pathogenesis of cardiovascular disease. Smooth …

Identification of proteins associating with glycosylphosphatidylinositol-anchored T-cadherin on the surface of vascular endothelial cells: role for Grp78/BiP in T …

M Philippova, D Ivanov, MB Joshi… - … and cellular biology, 2008 - Am Soc Microbiol
There is scant knowledge regarding how cell surface lipid-anchored T-cadherin (T-cad)
transmits signals through the plasma membrane to its intracellular targets. This study aimed …