Human surfactant protein SP-A1 and SP-A2 variants differentially affect the alveolar microenvironment, surfactant structure, regulation and function of the alveolar …
J Floros, N Thorenoor, N Tsotakos… - Frontiers in …, 2021 - frontiersin.org
The human innate host defense molecules, SP-A1 and SP-A2 variants, differentially affect
survival after infection in mice and in lung transplant patients. SP-A interacts with the …
survival after infection in mice and in lung transplant patients. SP-A interacts with the …
How cell migration helps immune sentinels
MG Delgado, AM Lennon-Duménil - Frontiers in Cell and …, 2022 - frontiersin.org
The immune system relies on the migratory capacity of its cellular components, which must
be mobile in order to defend the host from invading micro-organisms or malignant cells. This …
be mobile in order to defend the host from invading micro-organisms or malignant cells. This …
Surfactant protein-A function: Knowledge gained from SP-A knockout mice
L Depicolzuane, DS Phelps, J Floros - Frontiers in Pediatrics, 2022 - frontiersin.org
Pulmonary surfactant proteins have many roles in surfactant-related functions and innate
immunity. One of these proteins is the surfactant protein A (SP-A) that plays a role in both …
immunity. One of these proteins is the surfactant protein A (SP-A) that plays a role in both …
[HTML][HTML] Biological sex influences susceptibility to Acinetobacter baumannii pneumonia in mice
Acinetobacter baumannii (A. baumannii) is an extremely versatile multidrug-resistant
pathogen with a very high mortality rate; therefore, it has become crucial to understand the …
pathogen with a very high mortality rate; therefore, it has become crucial to understand the …
Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment …
N Thorenoor, TM Umstead, X Zhang… - Frontiers in …, 2018 - frontiersin.org
Surfactant protein A (SP-A) is involved in lung innate host defense and surfactant-related
functions. The human SFTPA1 and SFTPA2 genes encode SP-A1 and SP-2 proteins, and …
functions. The human SFTPA1 and SFTPA2 genes encode SP-A1 and SP-2 proteins, and …
Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex …
N Thorenoor, X Zhang, TM Umstead… - Respiratory …, 2018 - Springer
Abstract Background Surfactant Protein-A (SP-A) is a major protein component of surfactant
and plays a role in surfactant-related functions and innate immunity. Human SP-A consists of …
and plays a role in surfactant-related functions and innate immunity. Human SP-A consists of …
Neutrophil and macrophage response in Acinetobacter Baumannii Infection and their relationship to Lung Injury
Z Liu, W Xu - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Acinetobacter baumannii (AB) infection has become a threat to global public health. AB is
one of the main pathogens causing nosocomial infections, especially ventilator-associated …
one of the main pathogens causing nosocomial infections, especially ventilator-associated …
Age-dependent increase of cytoskeletal components in sensory axons in human skin
Aging is a complex process characterized by several molecular and cellular imbalances.
The composition and stability of the neuronal cytoskeleton is essential for the maintenance …
The composition and stability of the neuronal cytoskeleton is essential for the maintenance …
The importance of redox status in the frame of lifestyle approaches and the genetics of the lung innate immune molecules, SP-A1 and SP-A2, on differential outcomes …
F Tekos, Z Skaperda, N Goutzourelas, DS Phelps… - Antioxidants, 2020 - mdpi.com
The pandemic of COVID-19 is of great concern to the scientific community. This mainly
affects the elderly and people with underlying diseases. People with obesity are more likely …
affects the elderly and people with underlying diseases. People with obesity are more likely …
SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved
GT Noutsios, N Thorenoor, X Zhang, DS Phelps… - Biology of sex …, 2017 - Springer
Background Human innate host defense molecules, surfactant protein A1 (SP-A1), and SP-
A2 differentially affect the function and proteome of the alveolar macrophage (AM). We …
A2 differentially affect the function and proteome of the alveolar macrophage (AM). We …