Organization of chromosomal DNA by SMC complexes

S Yatskevich, J Rhodes, K Nasmyth - Annual review of genetics, 2019 - annualreviews.org
Structural maintenance of chromosomes (SMC) complexes are key organizers of
chromosome architecture in all kingdoms of life. Despite seemingly divergent functions, such …

Towards a unified model of SMC complex function

M Hassler, IA Shaltiel, CH Haering - Current Biology, 2018 - cell.com
Protein complexes built of structural maintenance of chromosomes (SMC) and kleisin
subunits, including cohesin, condensin and the Smc5/6 complex, are master organizers of …

A folded conformation of MukBEF and cohesin

F Bürmann, BG Lee, T Than, L Sinn… - Nature structural & …, 2019 - nature.com
Structural maintenance of chromosomes (SMC)–kleisin complexes organize chromosomal
DNAs in all domains of life, with key roles in chromosome segregation, DNA repair and …

The condensin holocomplex cycles dynamically between open and collapsed states

JK Ryu, AJ Katan, EO van der Sluis, T Wisse… - Nature structural & …, 2020 - nature.com
Structural maintenance of chromosome (SMC) protein complexes are the key organizers of
the spatiotemporal structure of chromosomes. The condensin SMC complex has recently …

Molecular basis for SMC rod formation and its dissolution upon DNA binding

YM Soh, F Bürmann, HC Shin, T Oda, KS Jin… - Molecular cell, 2015 - cell.com
SMC condensin complexes are central modulators of chromosome superstructure in all
branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a …

The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes

S Nolivos, D Sherratt - FEMS microbiology reviews, 2014 - academic.oup.com
Abstract Structural Maintenance of Chromosomes (SMC) protein complexes are found in all
three domains of life. They are characterized by a distinctive and conserved architecture in …

Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems

A Krishnan, AM Burroughs, LM Iyer… - Nucleic acids …, 2020 - academic.oup.com
ABC ATPases form one of the largest clades of P-loop NTPase fold enzymes that catalyze
ATP-hydrolysis and utilize its free energy for a staggering range of functions from transport to …

Condensin, chromatin crossbarring and chromosome condensation

R Thadani, F Uhlmann, S Heeger - Current Biology, 2012 - cell.com
The processes underlying the large-scale reorganisation of chromatin in mitosis that form
compact mitotic chromosomes and ensure the fidelity of chromosome segregation during …

Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction

Y Li, NK Stewart, AJ Berger, S Vos… - Proceedings of the …, 2010 - National Acad Sciences
In contrast to the current state of knowledge in the field of eukaryotic chromosome
segregation, relatively little is known about the mechanisms coordinating the appropriate …

Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins

JJ Griese, G Witte, KP Hopfner - Nucleic acids research, 2010 - academic.oup.com
Abstract Structural Maintenance of Chromosomes (SMC) proteins are vital for a wide range
of processes including chromosome structure and dynamics, gene regulation and DNA …