Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

Abstract Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide
and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α …

Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

Diabetes is one of the major diseases worldwide and is the third leading cause of death in
the United States. Anti-diabetic drugs are used in the treatment of diabetes mellitus to control …

In this study, potent coumarin derivatives containing oxime ester 1∼ 28 as α-glucosidase
inhibitors were developed through a stepwise structure optimization, and the structure …

Green tea may favorably modulate blood glucose homeostasis, and regular consumption of
green tea can prevent the development of type 2 diabetes mellitus. In this study, α …

Over the past few years, the number of people diagnosed with type 2 diabetes has
increased owing to an unhealthy diet, a limited amount of exercise, and obesity. The search …

We have synthesized seventeen Coumarin based derivatives (1–17), characterized by 1
HNMR, 13 CNMR and EI-MS and evaluated for α-glucosidase inhibitory potential. Among …

This work aimed to synthesize a safe antimicrobial agent based on dihydroquinoxalinedione
derivatives. The structure of the synthesized compounds was established based on different …

The use of anti-diabetic drugs has been increasing worldwide and the evolution of
therapeutics has been enormous. Still, the currently available anti-diabetic drugs do not …