Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2
diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations …

Small‐fiber neuropathy (SFN) is a disorder of thinly myelinated Aδ and unmyelinated C
fibers. SFN is clinically dominated by neuropathic pain and autonomic complaints, leading to …

ABSTRACT The American Association of Clinical Endocrinologists/American College of
Endocrinology Medical Guidelines for Clinical Practice are systematically developed …

OBJECTIVE Diabetic peripheral neuropathy (DPN) has hitherto been considered a disease
of the peripheral nervous system only, with central nervous system (CNS) involvement …

Sudorimetry technology has evolved dramatically, as a rapid, non-invasive, robust, and
accurate biomarker for small fibers that can easily be integrated into clinical practice …

Purpose Diabetic peripheral neuropathy (DPN) is the most common complication of
diabetes. Small and large peripheral nerve fibers can be involved in DPN. Large nerve fiber …

Awareness of SFN and related symptoms is of great clinical relevance. Guidelines for
appropriate diagnostic workup using a stepwise approach involving a combination of tests …

Introduction Contact heat evoked potentials (CHEPs) may be an objective, non‐invasive
diagnostic tool in small‐fiber neuropathy (SFN). This study establishes normal CHEP values …

There has been a significant increase over recent years in the use of contact heat evoked
potentials (CHEPs) for the evaluation of small nerve fiber function. Measuring CHEP …

Clinical neurophysiologic investigation of pain pathways in humans is based on specific
techniques and approaches, since conventional methods of nerve conduction studies and …