Cutibacterium acnes as an Opportunistic Pathogen: An Update of Its Virulence-Associated Factors

C Mayslich, PA Grange, N Dupin - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is a member of the skin microbiota found predominantly in regions rich
in sebaceous glands. It is involved in maintaining healthy skin and has long been …

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
The anaerobic bacterium Propionibacterium acnes is believed to play an important role in
the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our …

[HTML][HTML] A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics

MS Donia, P Cimermancic, CJ Schulze, LCW Brown… - Cell, 2014 - cell.com
In complex biological systems, small molecules often mediate microbe-microbe and microbe-
host interactions. Using a systematic approach, we identified 3,118 small-molecule …

[PDF][PDF] Anatomy promotes neutral coexistence of strains in the human skin microbiome

A Conwill, AC Kuan, R Damerla, AJ Poret, JS Baker… - Cell Host & Microbe, 2022 - cell.com
What enables strains of the same species to coexist in a microbiome? Here, we investigate
whether host anatomy can explain strain co-residence of Cutibacterium acnes, the most …

A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles

J Claesen, JB Spagnolo, SF Ramos, KL Kurita… - Science translational …, 2020 - science.org
The composition of the skin microbiota varies widely among individuals when sampled at
the same body site. A key question is which molecular factors determine strain-level …

Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization

I Sharon, MJ Morowitz, BC Thomas… - Genome …, 2013 - genome.cshlp.org
The gastrointestinal microbiome undergoes shifts in species and strain abundances, yet
dynamics involving closely related microorganisms remain largely unknown because most …

Linking diet to acne metabolomics, inflammation, and comedogenesis: an update

BC Melnik - Clinical, cosmetic and investigational dermatology, 2015 - Taylor & Francis
Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to
Western diet. Three major food classes that promote acne are: 1) hyperglycemic …

Propionibacterium acnes: from commensal to opportunistic biofilm-associated implant pathogen

Y Achermann, EJC Goldstein, T Coenye… - Clinical microbiology …, 2014 - Am Soc Microbiol
Propionibacterium acnes is known primarily as a skin commensal. However, it can present
as an opportunistic pathogen via bacterial seeding to cause invasive infections such as …

Bacterial skin commensals and their role as host guardians

GJM Christensen, H Brüggemann - Beneficial microbes, 2014 - wageningenacademic.com
Recent years' investigations of the co-evolution and functional integration of the human body
and its commensal microbiota have disclosed that the microbiome has a major impact on …

Propionibacterium acnes: An Underestimated Pathogen in Implant‐Associated Infections

ME Portillo, S Corvec, O Borens… - BioMed research …, 2013 - Wiley Online Library
The role of Propionibacterium acnes in acne and in a wide range of inflammatory diseases
is well established. However, P. acnes is also responsible for infections involving implants …