Protein phosphatase 2A (PP2A) comprises a family of serine/threonine phosphatases,
minimally containing a well conserved catalytic subunit, the activity of which is highly …

The phosphorylation state of any protein represents a balance of the actions of specific
protein kinases and protein phosphatases. Many protein phosphatases are highly enriched …

Tumours progress despite being infiltrated by tumour-specific effector T cells. Tumours
contain areas of cellular necrosis, which are associated with poor survival in a variety of …

Abstract Protein phosphatase 2A (PP2A) is a principal Ser/Thr phosphatase, the
deregulation of which is associated with multiple human cancers, Alzheimer's disease and …

The PR65/A subunit of protein phosphatase 2A serves as a scaffolding molecule to
coordinate the assembly of the catalytic subunit and a variable regulatory B subunit …

Since abnormal tau phosphorylation may play a role in neurofibrillary tangle (NFT) formation
in aging and Alzheimer's disease (AD), we probed the distribution and abundance of protein …

Dynamic phosphorylation and dephosphorylation of proteins are fundamental mechanisms
utilized by cells to transduce signals. Whereas transduction by protein kinases has been a …

Protein phosphatase 2A describes an extended family of intracellular protein
serine/threonine phosphatases sharing a common catalytic subunit that regulates a variety …

Protein phosphatase 2A (PP2A) plays a prominent role in controlling accumulation of the
proto-oncoprotein c-Myc. PP2A mediates its effects on c-Myc by dephosphorylating a …

Small conductance Ca2+-activated K+ channels (SK channels) are complexes of four α pore-
forming subunits each bound by calmodulin (CaM) that mediate Ca2+ gating. Proteomic …