Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

Hepatitis B virus-associated hepatocellular carcinoma

GEM Rizzo, G Cabibbo, A Craxì - Viruses, 2022 - mdpi.com
Hepatitis B virus (HBV) is DNA-based virus, member of the Hepadnaviridae family, which
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …

Epidemiological trends and trajectories of MAFLD-associated hepatocellular carcinoma 2002–2033: the ITA. LI. CA database

A Vitale, G Svegliati-Baroni, A Ortolani, M Cucco… - Gut, 2023 - gut.bmj.com
Background Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a new
inclusive definition of the whole spectrum of liver diseases associated to metabolic …

Hepatocellular carcinoma in chronic viral hepatitis: where do we stand?

FP Russo, A Zanetto, E Pinto, S Battistella… - International journal of …, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death.
Although the burden of alcohol-and NASH-related HCC is growing, chronic viral hepatitis …

Optimizing systemic therapy for advanced hepatocellular carcinoma: the key role of liver function

G Cabibbo, A Aghemo, Q Lai, M Masarone… - Digestive and Liver …, 2022 - Elsevier
The number of effective systemic therapies for the treatment of advanced hepatocellular
carcinoma (HCC) is rapidly increasing, and the advent of immunotherapy has changed the …

From NAFLD to MAFLD: definition, pathophysiological basis and cardiovascular implications

A Boccatonda, L Andreetto, D D'Ardes, G Cocco… - Biomedicines, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is defined as a chronic liver disease characterized
by excessive fat accumulation in the liver without another obvious cause (no excessive …

[HTML][HTML] Blood biomarkers predict outcomes in patients with hepatocellular carcinoma treated with immune checkpoint Inhibitors: A pooled analysis of 44 retrospective …

L Zhang, J Feng, T Kuang, D Chai, Z Qiu… - International …, 2023 - Elsevier
Objective We conducted the first meta-analysis to identify the predictive significance of
baseline blood biomarkers (such as neutrophil to lymphocyte ratio (NLR), early alpha …

Incidence and predictors of hepatocellular carcinoma in patients with autoimmune hepatitis

F Colapietro, P Maisonneuve, E Lytvyak, U Beuers… - Journal of …, 2024 - Elsevier
Background and Aims Autoimmune hepatitis (AIH) is a rare chronic liver disease of unknown
aetiology; the risk of hepatocellular carcinoma (HCC) remains unclear and risk factors are …

The relationship between the use of metformin and the risk of pancreatic cancer in patients with diabetes: a systematic review and meta-analysis

J Hu, HD Fan, JP Gong, QS Mao - BMC gastroenterology, 2023 - Springer
Objective We aim to evaluate the relationship between the use of metformin and the risk of
pancreatic cancer in type 2 diabetes patients. Method We systematically searched the …

Pathogenesis of hepatocellular carcinoma: the interplay of apoptosis and autophagy

E Kouroumalis, I Tsomidis, A Voumvouraki - Biomedicines, 2023 - mdpi.com
The pathogenesis of hepatocellular carcinoma (HCC) is a multifactorial process that has not
yet been fully investigated. Autophagy and apoptosis are two important cellular pathways …