The unmapped chemical complexity of our diet

AL Barabási, G Menichetti, J Loscalzo - Nature Food, 2020 - nature.com
Our understanding of how diet affects health is limited to 150 key nutritional components that
are tracked and catalogued by the United States Department of Agriculture and other …

Comparative toxicogenomics database (CTD): update 2021

AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2021 - academic.oup.com
Abstract The public Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is an
innovative digital ecosystem that relates toxicological information for chemicals, genes …

Comparative toxicogenomics database (CTD): update 2023

AP Davis, TC Wiegers, RJ Johnson… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) harmonizes
cross-species heterogeneous data for chemical exposures and their biological …

The comparative toxicogenomics database: update 2019

AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …

The comparative toxicogenomics database: update 2017

AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2017 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) provides
information about interactions between chemicals and gene products, and their …

CTD tetramers: a new online tool that computationally links curated chemicals, genes, phenotypes, and diseases to inform molecular mechanisms for environmental …

AP Davis, TC Wiegers, J Wiegers, B Wyatt… - Toxicological …, 2023 - academic.oup.com
The molecular mechanisms connecting environmental exposures to adverse endpoints are
often unknown, reflecting knowledge gaps. At the Comparative Toxicogenomics Database …

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

AP Davis, CJ Grondin, K Lennon-Hopkins… - Nucleic acids …, 2015 - academic.oup.com
Ten years ago, the Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) was
developed out of a need to formalize, harmonize and centralize the information on …

Progress in data interoperability to support computational toxicology and chemical safety evaluation

S Watford, S Edwards, M Angrish, RS Judson… - Toxicology and applied …, 2019 - Elsevier
New approach methodologies (NAMs) in chemical safety evaluation are being explored to
address the current public health implications of human environmental exposures to …

[HTML][HTML] Predicting molecular mechanisms, pathways, and health outcomes induced by Juul e-cigarette aerosol chemicals using the Comparative Toxicogenomics …

CJ Grondin, AP Davis, JA Wiegers, TC Wiegers… - Current research in …, 2021 - Elsevier
There is a critical need to understand the health risks associated with vaping e-cigarettes,
which has reached epidemic levels among teens. Juul is currently the most popular type of e …

[HTML][HTML] Predicting potential drugs for breast cancer based on miRNA and tissue specificity

L Yu, J Zhao, L Gao - International journal of biological sciences, 2018 - ncbi.nlm.nih.gov
Network-based computational method, with the emphasis on biomolecular interactions and
biological data integration, has succeeded in drug development and created new directions …