Neuromodulation of spike-timing-dependent plasticity: past, present, and future

Z Brzosko, SB Mierau, O Paulsen - Neuron, 2019 - cell.com
Spike-timing-dependent synaptic plasticity (STDP) is a leading cellular model for behavioral
learning and memory with rich computational properties. However, the relationship between …

Synaptic functions of endocannabinoid signaling in health and disease

A Araque, PE Castillo, OJ Manzoni, R Tonini - Neuropharmacology, 2017 - Elsevier
Endocannabinoids (eCBs) are a family of lipid molecules that act as key regulators of
synaptic transmission and plasticity. They are synthetized “on demand” following …

Dysfunction of the corticostriatal pathway in autism spectrum disorders

W Li, L Pozzo‐Miller - Journal of neuroscience research, 2020 - Wiley Online Library
The corticostriatal pathway that carries sensory, motor, and limbic information to the striatum
plays a critical role in motor control, action selection, and reward. Dysfunction of this …

Mechanisms of endocannabinoid control of synaptic plasticity

BL Winters, CW Vaughan - Neuropharmacology, 2021 - Elsevier
The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …

Functional relevance of endocannabinoid-dependent synaptic plasticity in the central nervous system

SM Augustin, DM Lovinger - ACS chemical neuroscience, 2018 - ACS Publications
The endocannabinoid (eCB) signaling system plays a key role in short-term and long-term
synaptic plasticity in brain regions involved in various neural functions ranging from action …

Cannabis: a treasure trove or pandora's box?

K Solymosi, A Köfalvi - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …

[HTML][HTML] Bridging the gap between striatal plasticity and learning

E Perrin, L Venance - Current opinion in neurobiology, 2019 - Elsevier
Highlights•Hebbian protocols induce bidirectional plasticity (LTP and LTD) in the
striatum.•Multiple pathways interact to induce activity-dependent STDP in the …

The effect of tourist destination image (TDI) on intention to visit through tourism risk perception (TRP) of COVID-19 in the tourism industry in the new normal era in …

CE Susanti, YB Hermanto, B Suwito - Journal of Risk and Financial …, 2023 - mdpi.com
The travel industry was the first and most affected by the pandemic. Different countries took
action to limit the spread of the coronavirus disease, including total or partial lockdowns and …

Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses

I Martínez-Gallego, H Coatl-Cuaya… - Elife, 2024 - elifesciences.org
The entorhinal cortex (EC) connects to the hippocampus sending different information from
cortical areas that is first processed at the dentate gyrus (DG) including spatial, limbic and …

Modulation of spike-timing dependent plasticity: towards the inclusion of a third factor in computational models

A Foncelle, A Mendes… - Frontiers in …, 2018 - frontiersin.org
In spike-timing dependent plasticity (STDP) change in synaptic strength depends on the
timing of pre-vs. postsynaptic spiking activity. Since STDP is in compliance with Hebb's …