Recent advances in dendrimer-based nanoplatform for cancer treatment: A review

RS Ambekar, M Choudhary… - European polymer …, 2020 - Elsevier
Out of the total deaths, 70% death occurs in middle and low-income countries due to cancer
and according to world cancer report 2014, total annual economic cost of cancer in 2010 …

Dendrimer as a promising nanocarrier for the delivery of doxorubicin as an anticancer therapeutics

V Singh, P Kesharwani - Journal of Biomaterials Science, Polymer …, 2021 - Taylor & Francis
Dendrimers are macromolecules with high-polymeric branching capable of undergoing
major modifications. These characteristics make them an efficient nanocarrier capable of …

A combinatorial delivery of survivin targeted siRNA using cancer selective nanoparticles for triple negative breast cancer therapy

P Kesharwani, A Sheikh, MAS Abourehab… - Journal of Drug Delivery …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is one major type of cancer for which there has been
no effective therapy to date. An important reason for it being the lack of expression of …

Chitosan overlaid Fe3O4/rGO nanocomposite for targeted drug delivery, imaging, and biomedical applications

V Karthika, MS AlSalhi, S Devanesan, K Gopinath… - Scientific Reports, 2020 - nature.com
A hybrid and straightforward nanosystem that can be used simultaneously for cancer-
targeted fluorescence imaging and targeted drug delivery in vitro was reported in this study …

Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury

R Sharma, SP Kambhampati, Z Zhang… - Journal of Controlled …, 2020 - Elsevier
Traumatic brain injury (TBI) is a significant medical problem with limited treatment options
and is one of the main causes of life-long disability. Neuroinflammation orchestrated by …

Simple preparation of maltose-functionalized dendrimer/graphene quantum dots as a pH-sensitive biocompatible carrier for targeted delivery of doxorubicin

S Karimi, H Namazi - International journal of biological macromolecules, 2020 - Elsevier
In the present study, a novel magnetic carbon modified with 3-aminopropyltrimethoxysilane
(APTMS) using maltose disaccharide molecule as a green capping agent, and a third …

Targeted delivery of doxorubicin into cancer cells using a folic acid–dendrimer conjugate

Y Wang, X Cao, R Guo, M Shen, M Zhang, M Zhu… - Polymer …, 2011 - pubs.rsc.org
We report here a general approach to using multifunctional poly (amidoamine)(PAMAM)
dendrimer-based platform to encapsulate an anticancer drug doxorubicin (DOX) for targeted …

[HTML][HTML] Review on the binding of anticancer drug doxorubicin with DNA and tRNA: Structural models and antitumor activity

D Agudelo, P Bourassa, G Bérubé… - … of Photochemistry and …, 2016 - Elsevier
In this review, we have compared the results of multiple spectroscopic studies and molecular
modeling of anticancer drug doxorubicin (DOX) bindings to DNA and tRNA. DOX was …

Peganum harmala Alkaloids and Tannic Acid Encapsulated in PAMAM Dendrimers: Improved Anticancer Activities as Compared to Doxorubicin

HMES Azzazy, AM Sawy, A Abdelnaser… - ACS Applied Polymer …, 2022 - ACS Publications
pH-responsive dual-loaded nanoplatforms based on polyamidoamine dendrimer with a
hydroxyl-terminated surface (PAMAM–OH), generations 3, 4, and 5 (G3, G4, and G5 …

Tea polyphenols bind serum albumins: A potential application for polyphenol delivery

P Chanphai, HA Tajmir-Riahi - Food Hydrocolloids, 2019 - Elsevier
Serum proteins play an important role as drug delivery in the clinical applications. We have
determined the binding efficacy of tea catechins (+)-catechin (C),(−)-epicatechin gallate …