Tackling the emerging threat of antifungal resistance to human health

MC Fisher, A Alastruey-Izquierdo, J Berman… - Nature reviews …, 2022 - nature.com
Invasive fungal infections pose an important threat to public health and are an under-
recognized component of antimicrobial resistance, an emerging crisis worldwide. Across a …

Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Candida auris Genetics and Emergence

A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …

Treatment strategies for cryptococcal infection: challenges, advances and future outlook

KR Iyer, NM Revie, C Fu, N Robbins… - Nature Reviews …, 2021 - nature.com
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016

MA Pfaller, DJ Diekema, JD Turnidge… - Open forum …, 2019 - academic.oup.com
Background The emergence of antifungal resistance threatens effective treatment of
invasive fungal infection (IFI). Invasive candidiasis is the most common health care …

[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

The global problem of antifungal resistance: prevalence, mechanisms, and management

DS Perlin, R Rautemaa-Richardson… - The Lancet infectious …, 2017 - thelancet.com
All serious fungal infections need appropriate antifungal therapy for successful patient
outcome. Only a few classes of antifungal drugs are available, so the emergence of …

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

Antimicrobial metal nanomaterials: from passive to stimuli‐activated applications

S Cheeseman, AJ Christofferson, R Kariuki… - Advanced …, 2020 - Wiley Online Library
The development of antimicrobial drug resistance among pathogenic bacteria and fungi is
one of the most significant health issues of the 21st century. Recently, advances in …

[HTML][HTML] The antifungal pipeline: a reality check

JR Perfect - Nature reviews Drug discovery, 2017 - nature.com
Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …