MRI plays a central role in the diagnosis of multiple sclerosis (MS) and in the monitoring of
disease course and treatment response. Advanced MRI techniques have shed light on MS …

A promising clinical trial utilizing gold-silica core-shell nanostructures coated with
polyethylene glycol (PEG) has been reported for near-infrared (NIR) photothermal therapy …

Background Conventional brain magnetic resonance imaging (MRI) produces image
intensities that have an arbitrary scale, hampering quantification. Intensity scaling aims to …

Objectives To evaluate white matter and grey matter T1-weighted (w)/T2w ratio (T1w/T2w
ratio) in healthy controls and patients with multiple sclerosis, and its association with clinical …

Abstract Background T1w/T2-w ratio has been proposed as a clinically feasible MRI
biomarker to assess tissue integrity in multiple sclerosis. However, no data is available in the …

Amyloid-beta (Aβ) aggregates and myelin breakdown are among the earliest detrimental
effects of Alzheimer's disease (AD), likely inducing abnormal patterns of neuronal …

Background Network-based measures are emerging MRI markers in multiple sclerosis (MS).
We aimed to identify networks of white (WM) and grey matter (GM) damage that predict …

Background Living in a disadvantaged neighborhood is associated with worse health
outcomes, including brain health, yet the underlying biological mechanisms are …

In the last decade, ratio maps derived from T1-weighted (T1w) and T2-weighted (T2w)
magnetic resonance imaging (MRI) sequences have been increasingly used particularly to …

Background Non-modifiable risk factors of Alzheimer's disease (AD) have lifelong effects on
cortical integrity that could be mitigated if identified at early stages. However, it remains …