Overview of bioactive fungal secondary metabolites: cytotoxic and antimicrobial compounds

R Conrado, TC Gomes, GSC Roque, AO De Souza - Antibiotics, 2022 - mdpi.com
Microorganisms are known as important sources of natural compounds that have been
studied and applied for different purposes in distinct areas. Specifically, in the …

Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.

G Chi, Y Xu, X Cao, Z Li, M Cao, Y Chisti, N He - Biotechnology advances, 2022 - Elsevier
Diverse health benefits are associated with dietary consumption of omega-3 long-chain
polyunsaturated fatty acids (ω-3 LC-PUFA), particularly docosahexaenoic acid (DHA) and …

Production, immobilization and characterization of beta-glucosidase for application in cellulose degradation from a novel Aspergillus versicolor

C Huang, Y Feng, G Patel, X Xu, J Qian, Q Liu… - International Journal of …, 2021 - Elsevier
Abstract Beta-glucosidase (EC 3.2. 1.21) catalyzes the hydrolysis of cellobiose and
cellooligosaccharides containing (1→ 4)-beta-glycosidic bonds to glucose, which is crucial …

Removal of nitrate and phosphate from simulated agricultural runoff water by Chlorella vulgaris

A Vazirzadeh, K Jafarifard, A Ajdari, Y Chisti - Science of The Total …, 2022 - Elsevier
Microalgae such Chlorella vulgaris can effectively absorb nitrate and phosphate from
contaminated water. This work characterized nitrate and phosphate removal from simulated …

Current advances of endophytes as a platform for production of anti-cancer drug camptothecin

Q Ruan, G Patel, J Wang, E Luo, W Zhou… - Food and Chemical …, 2021 - Elsevier
Abstract Camptothecin (CPT), a well-known monoterpenoid indole alkaloid with broad-
spectrum anti-cancer activity, is produced from plants and endophytes. In view of the …

Liposomal delivery of mycophenolic acid with quercetin for improved breast cancer therapy in SD rats

G Patel, NS Thakur, V Kushwah, MD Patil… - … in bioengineering and …, 2020 - frontiersin.org
The present study explores the influence of mycophenolic acid (MPA) in combination
therapy with quercetin (QC)(impeding MPA metabolic rate) delivered using the liposomal …

Mycophenolate co-administration with quercetin via lipid-polymer hybrid nanoparticles for enhanced breast cancer management

G Patel, NS Thakur, V Kushwah, MD Patil… - … , Biology and Medicine, 2020 - Elsevier
Mycophenolic acid (MPA) has promising anticancer properties; however, it has limited
clinical applications in vivo due to hydrophobic nature, high first-pass metabolism, lack of …

Strategies for supplying precursors to enhance the production of secondary metabolites in solid-state fermentation

JE Méndez-Hernández, LV Rodríguez-Durán… - Fermentation, 2023 - mdpi.com
The production of secondary metabolites can be improved with the supply of precursors both
in submerged and solid-state fermentation (SSF). Microorganisms assimilate the precursors …

Unlocking the biosynthetic potential of Penicillium roqueforti for hyperproduction of the immunosuppressant mycophenolic acid: Gamma radiation mutagenesis and …

ESR El‐Sayed, AG Zaki - Biotechnology and Applied …, 2023 - Wiley Online Library
Based on the broad clinical utility of the immunosuppressant mycophenolic acid (MPA), this
article aims to intensify the biosynthetic potential of Penicillium roqueforti for more effective …

A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment

K Wadhwa, N Kapoor, H Kaur, EA Abu-Seer, M Tariq… - Mycobiology, 2024 - Taylor & Francis
Fungi and their natural products, like secondary metabolites, have gained a huge demand in
the last decade due to their increasing applications in healthcare, environmental cleanup …