Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?

N Lepareur - Frontiers in Medicine, 2022 - frontiersin.org
Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

Dental Pulp Stem Cells for Salivary Gland Regeneration—Where Are We Today?

D Muallah, J Matschke, M Kappler… - International Journal of …, 2023 - mdpi.com
Xerostomia is the phenomenon of dry mouth and is mostly caused by hypofunction of the
salivary glands. This hypofunction can be caused by tumors, head and neck irradiation …

AAZTA-derived chelators for the design of innovative radiopharmaceuticals with theranostic applications

C Fersing, N Masurier, L Rubira, E Deshayes… - Pharmaceuticals, 2022 - mdpi.com
With the development of 68Ga and 177Lu radiochemistry, theranostic approaches in
modern nuclear medicine enabling patient-centered personalized medicine applications …

A Specific HPLC Method to Determine Residual HEPES in [68Ga]Ga-Radiopharmaceuticals: Development and Validation

S Migliari, M Scarlattei, G Baldari, C Silva, L Ruffini - Molecules, 2022 - mdpi.com
Background: Nowadays, in Nuclear Medicine, clinically applied radiopharmaceuticals must
meet quality release criteria such as high radiochemical purity and radiochemical yield …

N-Benzylethanolammonium Ionic Liquids and Molten Salts in the Synthesis of 68Ga- and Al18F-Labeled Radiopharmaceuticals

YA Kondratenko, JS Shilova, VA Gavrilov, AA Zolotarev… - Pharmaceutics, 2023 - mdpi.com
Ionic liquids (ILs), due to their structural features, have unique physical and chemical
properties and are environmentally friendly. Every year, the number of studies devoted to the …

Urease inhibition studies of two Cu (II) complexes with an ONO tridentate Schiff base and two different secondary ligands: An experimental, DFT, molecular docking …

H Wang, P Guo, Y Zhou, C Yin, Y Lei, R Wang… - Journal of Molecular …, 2024 - Elsevier
Two mononuclear Copper (II) complexes, identified as [Cu (C 10 H 8 NO 4 F)(C 6 H 7
N)](C1) and [Cu (C 10 H 8 NO 4 F)(C 12 H 8 N 2)]· H 2 O· CH 3 OH (C2), incorporating a …

The pharmaceutical technology approach on imaging innovations from Italian research

G Ailuno, RM Iacobazzi, A Lopalco, S Baldassari… - Pharmaceutics, 2021 - mdpi.com
Many modern therapeutic approaches are based on precise diagnostic evidence, where
imaging procedures play an essential role. To date, in the diagnostic field, a plethora of …

Bioactivity and computational studies on the induction of urease inhibition by three Cu (II) complexes with a fluorinated Schiff base and different secondary ligands

W Zhang, H Wang, C Ding, Y Lei, C Yin, R Wang… - Inorganic Chemistry …, 2024 - Elsevier
Three mononuclear Cu (II) complexes,[Cu (C 16 H 12 NO 3 F)(H 2 O)](C1),[Cu (C 16 H 12
NO 3 F)(C 10 H 9 N 3)]· H 2 O· 0.5 CH 3 OH (C2) and [Cu (C 16 H 12 NO 3 F)(C 3 H 4 N …

Evaluation of acute intravenous toxicity of HEPES: Is Good's buffer good and safe enough for clinical utilization in nuclear medicine?

M Guleria, KJ Pallavi, PP Gujarathi, T Das - Nuclear Medicine and Biology, 2024 - Elsevier
Objective Good's buffer or HEPES has advantages over other buffers commonly used in
radiopharmaceutical preparation as it exhibits significantly lower complexation tendency …

Automated radiosynthesis of pharmaceutical grade [68Ga]Ga-NODAGA-Lys40-Exendin-4 and demonstration of its efficacy for use in patients

SR Menon, A Mitra, A Chakraborty, Kamaldeep… - … of Radioanalytical and …, 2024 - Springer
The radiosynthesis of pharmaceutical grade [68Ga] Ga-NODAGA-Lys40-Exendin-4 was
accomplished in a fixed tubing-based module, EZ Modular-Lab Standard. Purification of the …