Phytosterol of lotus seed core powder alleviates hypercholesterolemia by regulating gut microbiota in high-cholesterol diet-induced C57BL/6J mice

D Liu, J Pi, B Zhang, H Zeng, C Li, Z Xiao, F Fang… - Food Bioscience, 2023 - Elsevier
The present study aimed to investigate the regulatory mechanisms of lotus seed core
powder phytosterol extract (LSP-PE) on hypercholesterolemia and intestinal microbiota in …

Resistance to cholesterol gallstone disease: hepatic cholesterol metabolism

C Zhang, W Dai, S Yang, S Wu… - The Journal of Clinical …, 2024 - academic.oup.com
Cholesterol gallstone disease (CGD) is one of the most common digestive diseases, and it is
closely associated with hepatic cholesterol metabolism. Cholesterol gallstones may be …

[HTML][HTML] Traditional Chinese medicine for lipid metabolism disorders

Y Li, X Wang, Z Shen - American Journal of Translational Research, 2017 - ncbi.nlm.nih.gov
Dyslipidemia significantly contributes to the development of cardiovascular disease (CVD),
which is the most common cause of morbidity and mortality in China. Statins are the first-line …

[HTML][HTML] Novel milk casein–derived peptides decrease cholesterol micellar solubility and cholesterol intestinal absorption in Caco-2 cells

X Jiang, D Pan, T Zhang, C Liu, J Zhang, M Su… - Journal of dairy …, 2020 - Elsevier
This study sought to assess the cholesterol-lowering activity of peptides obtained from milk
casein hydrolyzed with neutrase. The bioactive peptides were separated using a Sephadex …

Cranberry anthocyanin as an herbal medicine lowers plasma cholesterol by increasing excretion of fecal sterols

L Wang, H Zhu, Y Zhao, R Jiao, L Lei, J Chen, X Wang… - Phytomedicine, 2018 - Elsevier
Background Interest in using herbal medicines to treat the hypercholesterolemia is
increasing. Cranberry extract could decrease plasma cholesterol, however, the active …

[HTML][HTML] Hepatic Niemann-Pick C1-Like 1 exacerbates non-alcoholic fatty liver disease by re-absorbing specific biliary oxysterols

Y Yamanashi, T Takada, Y Tanaka, Y Ogata… - Biomedicine & …, 2022 - Elsevier
Background Dietary oxysterols are believed to be associated with the progression of non-
alcoholic fatty liver disease (NAFLD). However, the molecular basis of the association …

Plasma cholesterol-lowering activity of dietary dihydrocholesterol in hypercholesterolemia hamsters

X Wang, L Guan, Y Zhao, L Lei, Y Liu, KY Ma, L Wang… - Atherosclerosis, 2015 - Elsevier
Objective Cholesterol analogs have been used to treat hypercholesterolemia. The present
study was to examine the effect of dihydrocholesterol (DC) on plasma total cholesterol (TC) …

Future therapeutic targets for the treatment and prevention of cholesterol gallstones

IG Castro-Torres… - European Journal of …, 2015 - Elsevier
The formation of cholesterol gallstones involves very complex imbalances, such as
alterations in the secretion of biliary lipids (which involves the ABCG5, ABCG8, ABCB4 and …

Fisiopatología de cálculos biliares de colesterol: la búsqueda de una diana terapéutica

IG Castro-Torres, IB Bermúdez-Camps - Revista Biomedica, 2015 - revistabiomedica.mx
En la fisiopatología de los cálculos biliares de colesterol se involucran diferentes desajustes
tales como, la alteración en la secreción de lípidos biliares, la cristalización o nucleación del …

以NPC1L1 为靶点治疗胆固醇结石的研究进展

陈露露, 周宏灏, 欧阳冬生 - 中国临床药理学与治疗学, 2015 - manu41.magtech.com.cn
胆固醇结石病因形成复杂, 涉及到胆汁脂类分泌的改变, 胆固醇结晶, 胆囊组织中的重要免疫反应
, 粘蛋白的形成以及胆囊动力不足等多个方面. 抑制肠道对胆固醇的吸收, 减少胆汁分泌是胆固醇 …