Does the vaginal microbiota play a role in the development of cervical cancer?

M Kyrgiou, A Mitra, AB Moscicki - Translational Research, 2017 - Elsevier
Persistent infection with oncogenic human papillomavirus (HPV) is necessary but not
sufficient for the development of cervical cancer. The factors promoting persistence as well …

HPV infection: immunological aspects and their utility in future therapy

E Deligeoroglou, A Giannouli… - … in obstetrics and …, 2013 - Wiley Online Library
High prevalence and mortality rates of cervical cancer create an imperative need to clarify
the uniqueness of HPV (Human Papillomavirus) infection, which serves as the key causative …

The influence of hormonal factors on the risk of developing cervical cancer and pre-cancer: results from the EPIC cohort

E Roura, N Travier, T Waterboer, S De Sanjosé… - PloS one, 2016 - journals.plos.org
Background In addition to HPV, high parity and hormonal contraceptives have been
associated with cervical cancer (CC). However, most of the evidence comes from …

Attitude towards HPV vaccination and the intention to get vaccinated among female university students in health schools in Jordan

M Sallam, K Al-Mahzoum, H Eid, AM Assaf… - Vaccines, 2021 - mdpi.com
Cervical cancer is a leading cause of morbidity and mortality in women worldwide. The
availability of prophylactic vaccines for high-risk types of human papillomavirus (HPV) …

Stress keratin 17 and estrogen support viral persistence and modulate the immune environment during cervicovaginal murine papillomavirus infection

W Wang, ME Spurgeon, A Pope… - Proceedings of the …, 2023 - National Acad Sciences
A murine papillomavirus, MmuPV1, infects both cutaneous and mucosal epithelia of
laboratory mice and can be used to model high-risk human papillomavirus (HPV) infection …

The immune microenvironment in human papilloma virus-induced cervical lesions—Evidence for estrogen as an immunomodulator

J Rs - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
Globally, human papilloma virus (HPV) infection is a common sexually transmitted disease.
However, most of the HPV infections eventually resolve aided by the body's efficient cell …

Epidemiology, molecular pathogenesis, immuno-pathogenesis, immune escape mechanisms and vaccine evaluation for HPV-associated carcinogenesis

M Jain, D Yadav, U Jarouliya, V Chavda, AK Yadav… - Pathogens, 2023 - mdpi.com
Human papillomavirus (HPV) is implicated in over 90% of cervical cancer cases, with factors
like regional variability, HPV genotype, the population studied, HPV vaccination status, and …

The relationship between hormonal contraception and cervical dysplasia/cancer controlling for human papillomavirus infection: A systematic review

E Anastasiou, KJ McCarthy, EL Gollub, L Ralph… - Contraception, 2022 - Elsevier
Objective Studies on the effect of long-term use of combined oral contraceptives (COCs) on
cervical dysplasia and/or cancer risk have been inconsistent. Less is known about the …

A study on the correlation between the prognosis of HPV infection and lesion recurrence after cervical conization

J Lu, S Han, Y Li, J Na, J Wang - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction Persistent human papillomavirus infection is an important factor in the
development of cervical cancer, which is usually a long process evolving from the …

Factors associated with non-participation in cervical cancer screening–a nationwide study of nearly half a million women in Denmark

E Harder, KE Juul, SM Jensen, LT Thomsen… - Preventive …, 2018 - Elsevier
Cervical cancer occurs most often in under-screened women. In this nationwide register
study, we described differences in sociodemographic characteristics between passive and …