C-type lectin-like receptors of the dectin-1 cluster: ligands and signaling pathways

A Plato, JA Willment, GD Brown - International reviews of …, 2013 - Taylor & Francis
Innate immunity is constructed around genetically encoded receptors that survey the
intracellular and extracellular environments for signs of invading microorganisms. These …

Cardiac troponin is the most effective translational safety biomarker for myocardial injury in cardiotoxicity

PJ O'Brien - Toxicology, 2008 - Elsevier
There is an overwhelming weight of evidence that certifies cardiac troponin (cTn) as the
preferred, defacto, translational, safety biomarker for myocardial injury in cardiotoxicity. As …

Doxorubicin Treatment in Vivo Causes Cytochrome c Release and Cardiomyocyte Apoptosis, As Well As Increased Mitochondrial Efficiency, Superoxide Dismutase …

AC Childs, SL Phaneuf, AJ Dirks, T Phillips… - Cancer research, 2002 - AACR
There have been very few investigations as to whether mitochondrial-mediated apoptosis in
vivo is the underlying mechanism of doxorubicin cardiotoxicity. Moreover, no investigations …

Cardiac troponin I is a sensitive, specific biomarker of cardiac injury in laboratory animals

PJ O'brien, DEC Smith, TJ Knechtel… - Laboratory …, 2006 - journals.sagepub.com
This study directly demonstrates that cardiac troponin I (cTnI) is a sensitive, specific, and
persistent biomarker in laboratory animals. Histopathological and pathophysiological …

Cardiac troponin‐I concentration in dogs with cardiac disease

MA Oyama, DD Sisson - Journal of veterinary internal medicine, 2004 - Wiley Online Library
Cardiac troponin‐I (cTnI) is a highly sensitive and specific marker of myocardial injury and
can be detected in plasma by immunoassay techniques. The purpose of this study was to …

[图书][B] Animal clinical chemistry: a practical handbook for toxicologists and biomedical researchers

GO Evans - 2009 - taylorfrancis.com
10+ Years of Updates Since First EditionNewcomers to the animal clinical chemistry and
toxicology fields quickly find that the same rules of human medicine do not always apply …

Human heart-type fatty acid-binding protein as an early diagnostic and prognostic marker in acute coronary syndrome

T Nakata, A Hashimoto, M Hase, K Tsuchihashi… - Cardiology, 2003 - karger.com
Although heart-type fatty acid-binding protein (H-FABP) can be a marker of sarcolemmal
injury due to acute myocardial ischemia, the diagnostic or prognostic value is not …

Correlation between serum levels of cardiac troponin-T and the severity of the chronic cardiomyopathy induced by doxorubicin

EH Herman, J Zhang, SE Lipshultz, N Rifai… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: To investigate, over a wide range of cumulative doxorubicin doses, the feasibility
of using serum concentrations of cardiac troponin-T (cTnT) as a biomarker for doxorubicin …

[HTML][HTML] Experimental model of myocardial infarction induced by isoproterenol in rats

HG Lobo Filho, NL Ferreira, RB Sousa… - Brazilian Journal of …, 2011 - SciELO Brasil
OBJETIVO: Avaliar e validar, em nosso meio, o modelo de infarto do miocárdio induzido por
isoproterenol em ratos por meio de análises de parâmetros hematológicos, bioquímicos, de …

Cardioprotective potential of N, α-l-rhamnopyranosyl vincosamide, an indole alkaloid, isolated from the leaves of Moringa oleifera in isoproterenol induced cardiotoxic …

S Panda, A Kar, P Sharma, A Sharma - Bioorganic & medicinal chemistry …, 2013 - Elsevier
Hitherto unknown protective effect of N, α-l-rhamnopyranosyl vincosamide (VR), isolated
from Moringa oleifera leaves in isoproterenol (ISO)-induced cardiac toxicity was evaluated in …