Detection and analysis of chiral molecules as disease biomarkers

Y Liu, Z Wu, DW Armstrong, H Wolosker… - Nature Reviews …, 2023 - nature.com
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

The food matrix: implications in processing, nutrition and health

JM Aguilera - Critical reviews in food science and nutrition, 2019 - Taylor & Francis
The concept of food matrix has received much attention lately in reference to its effects on
food processing, nutrition and health. However, the term matrix is used vaguely by food and …

Ms-based lipidomics of human blood plasma: A community-initiated position paper to develop accepted guidelines1

B Burla, M Arita, M Arita, AK Bendt… - Journal of lipid …, 2018 - ASBMB
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …

Metabolite concentration changes in humans after a bout of exercise: a systematic review of exercise metabolomics studies

D Schranner, G Kastenmüller, M Schönfelder… - Sports medicine …, 2020 - Springer
Background Exercise changes the concentrations of many metabolites, which are small
molecules (< 1.5 kDa) metabolized by the reactions of human metabolism. In recent years …

Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018 - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach

A Floegel, N Stefan, Z Yu, K Mühlenbruch, D Drogan… - Diabetes, 2013 - Am Diabetes Assoc
Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological
pathways and help to identify individuals at risk for disease. We prospectively investigated …

Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease

G Cadby, C Giles, PE Melton, K Huynh… - Nature …, 2022 - nature.com
We integrated lipidomics and genomics to unravel the genetic architecture of lipid
metabolism and identify genetic variants associated with lipid species putatively in the …

Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum

R Böttger, R Hoffmann, D Knappe - PloS one, 2017 - journals.plos.org
Proteolytic degradation of peptide-based drugs is often considered as major weakness
limiting systemic therapeutic applications. Therefore, huge efforts are typically devoted to …

Dissecting lipid metabolism alterations in SARS-CoV-2

I Casari, M Manfredi, P Metharom, M Falasca - Progress in lipid research, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …