Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

Non-alcoholic fatty liver disease (NAFLD) and its complications are an expanding health
problem associated with the metabolic syndrome. Liver sinusoidal endothelial cells (LSECs) …

Background & Aims Peroxisome proliferator-activated receptors (PPARs) are essential
regulators of whole-body metabolism, but also modulate inflammation in immune cells …

The role of angiogenesis in the growth of organs and tumors is widely recognized. Vascular–
organ interaction is a key mechanism and a concept that enables an understanding of all …

Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide. It is strongly associated with obesity, type 2 diabetes (T2DM), and other …

Liver fibrosis is a common feature of sustained liver injury and represents a major public
health problem worldwide. Fibrosis is an active research field and discoveries in the last …

Background & Aims Previous studies demonstrated that autophagy is protective in
hepatocytes and macrophages, but detrimental in hepatic stellate cells in chronic liver …

Introduction: Persistent inflammation and hypoxia are strong stimulus for pathological
angiogenesis and vascular remodeling, and are also the most important elements resulting …

Non-alcoholic fatty liver disease (NAFLD) is considered as the hepatic manifestation of
metabolic syndrome, which is characterised by obesity, insulin resistance …