The formation of vascular networks consisting of arteries, capillaries, and veins is vital in
embryogenesis. It is also crucial in adulthood for the formation of a functional vasculature …

Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …

Ferroptosis, as a form of cell death different from apoptosis, is very promising for the
treatment of cancer in nonapoptotic systems. Since iron is a key component in the induction …

Introduction Cancer is a big challenge of the 21 century, whose defeat requires efficient
antitumor drugs. Objectives The paper aims to investigate the synergistic effect of two …

Background: Colorectal cancer (CRC) is a highly widespread malignancy and ranks as the
second most common cause of cancer-related mortality. Objective: Cancer patients …

All-trans retinoic acid (ATRA) has promising activity against breast cancer. However, the
exact mechanisms of ATRA's anticancer effects remain complex and not fully understood. In …

Therapeutic vaccinations are designed to prevent cancer by inducing immune responses
against tumor antigens. in cancer cells, tumor-associated antigens (TAA) or tumor-specific …

Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 nucleotides.
Despite the fact that they cannot encode proteins, many studies have identified roles they …

The aberrant misfolding and self-aggregation of human islet amyloid polypeptide (hIAPP or
amylin) into cytotoxic aggregates are implicated in the pathogenesis of type 2 diabetes …

Colorectal cancer (CRC) is the second most common cause of cancer mortality, with
approximately 1.9 million new cases and 0.9 million deaths globally in 2020. One of the …