Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic
Adenoviral vectors have been explored as vaccine agents for a range of infectious diseases,
and their ability to induce a potent and balanced immune response made them logical …
and their ability to induce a potent and balanced immune response made them logical …
Current status of Zika virus vaccines: successes and challenges
The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …
[HTML][HTML] A single-dose intranasal ChAd vaccine protects upper and lower respiratory tracts against SARS-CoV-2
The coronavirus disease 2019 pandemic has made deployment of an effective vaccine a
global health priority. We evaluated the protective activity of a chimpanzee adenovirus …
global health priority. We evaluated the protective activity of a chimpanzee adenovirus …
COVID-19 vaccines and neglected pregnancy
On June 18, 2020, WHO presented a strategic framework to ensure the equitable allocation
of scarce COVID-19 resources, including vaccines. 1 Health-care workers, people older than …
of scarce COVID-19 resources, including vaccines. 1 Health-care workers, people older than …
CD8+ T cells mediate protection against Zika virus induced by an NS3-based vaccine
A Elong Ngono, T Syed, AV Nguyen… - Science …, 2020 - science.org
Zika virus (ZIKV) is associated with congenital malformations in infants born to infected
mothers, and with Guillain-Barré syndrome in infected adults. Development of ZIKV vaccines …
mothers, and with Guillain-Barré syndrome in infected adults. Development of ZIKV vaccines …
Landscape of monoclonal antibodies targeting zika and dengue: therapeutic solutions and critical insights for vaccine development
V Dussupt, K Modjarrad, SJ Krebs - Frontiers in immunology, 2021 - frontiersin.org
The unprecedented 2015–2016 Zika outbreak in the Americas sparked global concern and
drove the rapid deployment of vaccine and therapeutic countermeasures against this re …
drove the rapid deployment of vaccine and therapeutic countermeasures against this re …
A single dose of NILV-based vaccine provides rapid and durable protection against Zika virus
Zika virus, a member of the Flaviviridae family, is primarily transmitted by infected Aedes
species mosquitoes. In 2016, Zika infection emerged as a global health emergency for its …
species mosquitoes. In 2016, Zika infection emerged as a global health emergency for its …
A single and un-adjuvanted dose of a chimpanzee adenovirus-vectored vaccine against chikungunya virus fully protects mice from lethal disease
The mosquito-borne chikungunya virus (CHIKV) has become a major global health problem.
Upon infection, chikungunya fever (CHIKF) can result in long-term joint pain and arthritis …
Upon infection, chikungunya fever (CHIKF) can result in long-term joint pain and arthritis …
Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract
Zika virus (ZIKV) can cause devastating effects in the unborn fetus of pregnant women. To
develop a candidate vaccine that can protect human fetuses, we generated a panel of live …
develop a candidate vaccine that can protect human fetuses, we generated a panel of live …
New directions in pulmonary gene therapy
A Vu, PB McCray - Human gene therapy, 2020 - liebertpub.com
The lung has long been a target for gene therapy, yet efficient delivery and phenotypic
disease correction has remained challenging. Although there have been significant …
disease correction has remained challenging. Although there have been significant …