Targeting NK cell inhibitory receptors for precision multiple myeloma immunotherapy

H Alfarra, J Weir, S Grieve, T Reiman - Frontiers in immunology, 2020 - frontiersin.org
Innate immune surveillance of cancer involves multiple types of immune cells including the
innate lymphoid cells (ILCs). Natural killer (NK) cells are considered the most active ILC …

Understanding human immunity in idiopathic recurrent pregnancy loss

DB Dimakou, D Lissauer, J Tamblyn… - European Journal of …, 2022 - Elsevier
Miscarriage, defined as the loss of a pregnancy before a viable gestation, affects 1 in 6
couples. Recurrent pregnancy loss (RPL), defined as two or more miscarriages, affects up to …

[HTML][HTML] Psychological distress in women with recurrent spontaneous abortion: a case-control study

H Adib-Rad, Z Basirat, M Faramarzi… - Turkish journal of …, 2019 - ncbi.nlm.nih.gov
Objective: The aim of the present study was to evaluate psychological problems in women
with recurrent spontaneous abortion (RSA). Materials and Methods: In this case-control …

Recombinant human interleukin-2 corrects NK cell phenotype and functional activity in patients with post-COVID syndrome

AA Savchenko, IV Kudryavtsev, DV Isakov… - Pharmaceuticals, 2023 - mdpi.com
Post-COVID syndrome develops in 10–20% of people who have recovered from COVID-19
and it is characterized by impaired function of the nervous, cardiovascular, and immune …

[HTML][HTML] Hsp70, in combination with IL-15 and PD-1 blocker, interferes with the induction of cytotoxic NK cells in relapsed acute myeloid leukemia patients

J Firouzi, A Hajifathali, M Azimi, N Parvini… - Cell Journal …, 2023 - ncbi.nlm.nih.gov
Objective: Natural killer (NK) cells are critical immune cells for acute myeloid leukemia
(AML) targeting. However, little is known about the relationship between using checkpoint …

Immunology and ovarian cancers

WL Lee, PH Wang - Journal of the Chinese Medical Association, 2020 - journals.lww.com
The current standard therapy of epithelial ovarian cancer (EOC) is the combination of
surgery and multiagent chemotherapy with/without adding targeted therapy. After treatment …

Natural killer cells in sepsis: Friends or foes?

F Wang, Y Cui, D He, L Gong, H Liang - Frontiers in Immunology, 2023 - frontiersin.org
Sepsis is one of the major causes of death in the hospital worldwide. The pathology of
sepsis is tightly associated with dysregulation of innate immune responses. The contribution …

[HTML][HTML] The exploration of Hashimoto's Thyroiditis related miscarriage for better treatment modalities

Y Min, X Wang, H Chen, G Yin - International journal of medical …, 2020 - ncbi.nlm.nih.gov
Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disease (ATD)
worldwide and is strongly associated with miscarriage and even recurrent miscarriage (RM) …

Polarization disorder of decidual NK cells in unexplained recurrent spontaneous abortion revealed by single-cell transcriptome analysis

D Pan, Q Liu, L Du, Y Yang, G Jiang - Reproductive Biology and …, 2022 - Springer
Background Unexplained recurrent spontaneous abortion (URSA) is one of the most
common diseases in pregnancy and is mainly caused by immune disorders. The foetus is …

[HTML][HTML] A combination of immune cell types identified through ensemble machine learning strategy detects altered profile in recurrent pregnancy loss: a pilot study

M Benner, D Feyaerts, A Lopez-Rincon… - F&S Science, 2022 - Elsevier
Objective To compare the immunologic profiles of peripheral and menstrual blood (MB) of
women who experience recurrent pregnancy loss and women without pregnancy …