Pathological classification and molecular genetics of meningiomas
C Mawrin, A Perry - Journal of neuro-oncology, 2010 - Springer
Meningiomas are extremely common adult brain tumors originating from meningeal
coverings of the brain and spinal cord. While most are slowly growing Word Health …
coverings of the brain and spinal cord. While most are slowly growing Word Health …
The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications
SM Robert, S Vetsa, A Nadar, S Vasandani… - Journal of Neuro …, 2022 - Springer
Introduction Meningiomas are generally considered “benign,” however, these tumors can
demonstrate variability in behavior and a surprising aggressiveness with elevated rates of …
demonstrate variability in behavior and a surprising aggressiveness with elevated rates of …
Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells
H Wakimoto, G Mohapatra, R Kanai, WT Curry… - Neuro …, 2011 - academic.oup.com
The clinicopathological heterogeneity of glioblastoma (GBM) and the various genetic and
phenotypic subtypes in GBM stem cells (GSCs) are well described. However, the …
phenotypic subtypes in GBM stem cells (GSCs) are well described. However, the …
The role of radiotherapy following gross-total resection of atypical meningiomas
Object Atypical (WHO Grade II) meningiomas comprise a heterogeneous group of tumors,
with histopathology delineated under the guidance of the WHO and a spectrum of clinical …
with histopathology delineated under the guidance of the WHO and a spectrum of clinical …
A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma
AA Aizer, M Abedalthagafi, W Linda Bi… - Neuro …, 2015 - academic.oup.com
Background The appropriate use of adjuvant therapy in patients with gross totally resected
atypical meningioma requires an accurate assessment of recurrence risk. We sought to …
atypical meningioma requires an accurate assessment of recurrence risk. We sought to …
Revisiting adjuvant radiotherapy after gross total resection of World Health Organization grade II meningioma
CS Graffeo, HE Leeper, A Perry, JH Uhm… - World neurosurgery, 2017 - Elsevier
Background Atypical meningioma is a World Health Organization grade II tumor with
intermediate prognosis and risk of recurrence. Optimal management after gross total …
intermediate prognosis and risk of recurrence. Optimal management after gross total …
A functional copy-number variation in MAPKAPK2 predicts risk and prognosis of lung cancer
B Liu, L Yang, B Huang, M Cheng, H Wang, Y Li… - The American Journal of …, 2012 - cell.com
Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2) may promote
cancer development and progression by inducing tumorigenesis and drug resistance. To …
cancer development and progression by inducing tumorigenesis and drug resistance. To …
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers
SM Rothenberg, G Mohapatra, MN Rivera, D Winokur… - Cancer research, 2010 - AACR
In a genome-wide screen of 684 cancer cell lines, we identified homozygous intragenic
microdeletions involving genes encoding components of the apical-basal cell polarity …
microdeletions involving genes encoding components of the apical-basal cell polarity …
Atypical meningiomas
R Chen, MK Aghi - Handbook of clinical neurology, 2020 - Elsevier
Meningiomas are the most common primary CNS tumor in adults, representing a third of
brain lesions. Their clinical presentation varies greatly, ranging from asymptomatic …
brain lesions. Their clinical presentation varies greatly, ranging from asymptomatic …
Biology and clinical management challenges in meningioma
C Mawrin, C Chung, M Preusser - American Society of Clinical …, 2015 - ascopubs.org
Meningiomas are the most frequently occurring intracranial tumors. They are characterized
by a broad spectrum of histopathologic appearance. Molecular alterations driving …
by a broad spectrum of histopathologic appearance. Molecular alterations driving …