It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …

Placental-related fetal growth restriction arises primarily due to deficient remodeling of the
uterine spiral arteries supplying the placenta during early pregnancy. The resultant …

The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

The recently identified ferroptotic cell death is characterized by excessive accumulation of
hydroperoxy-arachidonoyl (C20: 4)-or adrenoyl (C22: 4)-phosphatidylethanolamine (Hp …

Oxidative stress (OS), an imbalance between free radical generation and antioxidant
defence, is recognized as a key factor in the pathogenesis of adverse pregnancy outcomes …

Physiological conversion of the maternal spiral arteries is key to a successful human
pregnancy. It involves loss of smooth muscle and the elastic lamina from the vessel wall as …

Preeclampsia, a systemic syndrome of pregnancy clinically characterized by new onset of
proteinuria and hypertension, is associated with significant morbidity and mortality to both …

BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Tissues are the new frontier of discoveries in immunology. Cells of the immune system are
an integral part of tissue physiology and immunity. Determining how immune cells inhabit …