Programmed cell death (PCD) is an essential component of animal development, and
aberrant cell death underlies many disorders. Understanding mechanisms that govern PCD …

RNA-binding proteins (RBPs) are essential for post-transcriptional regulation of gene
expression. Recent high-throughput screens have dramatically increased the number of …

Programmed cell death is critical to the development of diverse animal species from C.
elegans to humans. In C. elegans, the cell death program has three genetically …

Programmed cell death is an integral component of Caenorhabditis elegans development.
Genetic and reverse genetic studies in C. elegans have led to the identification of many …

The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the
assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated …

The proper regulation of apoptosis requires precise spatial and temporal control of gene
expression. While the transcriptional and translational activation of pro-apoptotic genes is …

The initiation of translation in eukaryotic cells is stimulated by proteins known as initiation
factors (eIFs). A structurally complex eIF composed of multiple subunits, eIF3 has been …

We investigated potential mechanisms of acute injury in pubertal mice testes after exposure
to carbon ion radiation (CIR). Serum testosterone was measured following whole-body …

Programmed cell death initiated by genotoxic stress requires signalling from surrounding
tissues, yet such mechanisms are poorly understood. The C. elegans germline is a powerful …

After transcription, mRNA translation is another highly regulated process in gene
expression. In plants, translation regulation plays an important role during progamic phase …